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高频电刀:一种用于治疗乳腺癌患者放射性毛细血管扩张的方法。

The hyfrecator: a treatment for radiation induced telangiectasia in breast cancer patients.

作者信息

Rowland Payne C M E, Somaiah N, Neal A J, Glees J P

机构信息

The London Clinic, London, St. George's Hospital, London, UK.

出版信息

Br J Radiol. 2005 Feb;78(926):143-6. doi: 10.1259/bjr/20164607.

Abstract

Radiation induced telangiectasia is a common problem in breast cancer survivors. By interfering with choice of clothing and acting as an unpleasant visible reminder of their disease, it negatively affects quality of life. The hyfrecator, based on the principles of electrosurgery, is a standard treatment modality for facial telangiectasia. This study aims to demonstrate the efficacy and tolerability of the hyfrecator as a treatment for radiation induced telangiectasia. Patients with radiation induced telangiectasia of breast or chest wall were prospectively identified from the breast cancer follow up clinic and offered treatment with the hyfrecator (sessions at 8 weekly intervals). Pre- and post-treatment photographs were obtained in a standardized manner and two blinded physician observers evaluated response. A linear analogue scale (LAS) was used by the patients to evaluate treatment response and any discomfort. At the end of treatment, patients completed a quality of life questionnaire. Of 16 patients enrolled, 15 completed the study. Treatment benefited all patients with severe or marked telangiectasia. Complete disappearance of telangiectasia was achieved in the majority (88%) of patients by the end of treatment. A median of six sessions (range 3-9) was required. All but one (93%) considered the treatment worthwhile. The majority (69%) judged the treatment to be painless or only mildly painful. 73% reported an improvement in self-confidence. The treatment was well tolerated by all the patients. All patients showed a remarkable clearance of vessels with a high degree of satisfaction with the results. Treatment with the hyfrecator is very effective for radiation induced telangiectasia. Three to four sessions achieve a substantial objective and subjective reduction in telangiectasia with a concomitant improvement in quality of life. It is a cost effective, ambulant out patient procedure requiring no local anaesthesia.

摘要

放射性毛细血管扩张是乳腺癌幸存者常见的问题。它会影响患者的着装选择,且作为疾病令人不快的明显表征,会对生活质量产生负面影响。基于电外科原理的高频电刀是治疗面部毛细血管扩张的标准治疗方式。本研究旨在证明高频电刀治疗放射性毛细血管扩张的疗效和耐受性。从乳腺癌随访门诊前瞻性地识别出患有乳腺或胸壁放射性毛细血管扩张的患者,并为其提供高频电刀治疗(每8周进行一次治疗)。以标准化方式获取治疗前后的照片,由两名不知情的医生观察者评估治疗反应。患者使用线性模拟量表(LAS)评估治疗反应和任何不适情况。治疗结束时,患者完成一份生活质量问卷。在纳入的16名患者中,15名完成了研究。治疗使所有患有严重或明显毛细血管扩张的患者受益。到治疗结束时,大多数(88%)患者的毛细血管扩张完全消失。治疗中位数为6次(范围3 - 9次)。除1人外,所有患者(93%)认为治疗是值得的。大多数患者(69%)认为治疗无痛或仅轻微疼痛。73%的患者报告自信心有所提高。所有患者对该治疗耐受性良好。所有患者的血管均有明显清除,对治疗结果高度满意。高频电刀治疗放射性毛细血管扩张非常有效。三到四次治疗可使毛细血管扩张在客观和主观上大幅减轻,同时改善生活质量。这是一种经济有效的门诊治疗方法,无需局部麻醉。

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