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脉冲染料激光治疗乳腺癌放疗后的毛细血管扩张症。

Pulsed dye laser treatment of telangiectasia after radiotherapy for carcinoma of the breast.

作者信息

Lanigan S W, Joannides T

机构信息

The Birmingham Skin Centre and Lasercare Clinic, City Hospital NHS Trust, Dudley Road, UK.

出版信息

Br J Dermatol. 2003 Jan;148(1):77-9. doi: 10.1046/j.1365-2133.2003.04861.x.

Abstract

BACKGROUND

Chronic radiodermatitis after radiotherapy for carcinoma of the breast is a common sequela of treatment and can be distressing for the patient. The skin is atrophic and shows prominent telangiectasia due to dilatation of a reduced or poorly supported skin vasculature. The pulsed dye laser (PDL) is an established treatment of cutaneous telangiectatic disorders including facial telangiectasia and spider naevi, and is safe and efficacious.

OBJECTIVES

To study the efficacy of the PDL in the treatment of postradiation telangiectasia of the breast or chest wall.

METHODS

Prospective open study of the treatment of eight females with the Candela SPTL1B PDL. Subjective assessments of vessel clearance, adverse effects and patient questionnaires.

RESULTS

All treated patients showed complete clearance of vessels. Two patients developed hypopigmentation. All patients reported a high degree of satisfaction with the treatment.

CONCLUSIONS

PDL therapy clears postirradiation telangiectasia of the breast and chest wall successfully with minimal adverse reactions, and can be recommended for patients distressed by this disorder.

摘要

背景

乳腺癌放疗后的慢性放射性皮炎是一种常见的治疗后遗症,会给患者带来困扰。由于皮肤血管系统减少或支撑不足而扩张,皮肤会出现萎缩并伴有明显的毛细血管扩张。脉冲染料激光(PDL)是治疗包括面部毛细血管扩张和蜘蛛痣在内的皮肤毛细血管扩张性疾病的既定疗法,且安全有效。

目的

研究脉冲染料激光治疗乳房或胸壁放疗后毛细血管扩张的疗效。

方法

对8名女性使用坎德拉SPTL1B脉冲染料激光进行前瞻性开放研究。对血管清除情况、不良反应进行主观评估并开展患者问卷调查。

结果

所有接受治疗的患者血管均完全清除。2例患者出现色素减退。所有患者对治疗均表示高度满意。

结论

脉冲染料激光疗法能成功清除乳房和胸壁放疗后的毛细血管扩张,不良反应最小,对于受此疾病困扰的患者值得推荐。

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