Bancroft K, Vaughan Williams C A, Elstein M
Department of Obstetrics and Gynaecology, University Hospital of South Manchester, UK.
Clin Endocrinol (Oxf). 1992 Feb;36(2):177-81. doi: 10.1111/j.1365-2265.1992.tb00954.x.
To determine whether abnormalities of pituitary-ovarian function are associated with minor degrees of endometriosis in women with otherwise unexplained infertility.
Comparison of pituitary-ovarian function in a group of 22 patients with that in a control group of 10 healthy fertile women.
Twenty-two women with minimal or mild endometriosis and otherwise unexplained infertility.
Ovarian ultrasound and radioimmunoassay of pituitary and ovarian hormones.
Abnormalities, including luteinization of unruptured follicles, broad LH surges and low concentrations of progesterone during the luteal phase, were demonstrated in 82% of study cycles.
Pituitary-ovarian dysfunction appears to be associated with minimal or mild endometriosis in women with otherwise unexplained infertility but the diversity of endocrine abnormalities demonstrated suggests that endometriosis is unlikely to be an aetiological factor in their development.
确定在其他方面原因不明的不孕症女性中，垂体 - 卵巢功能异常是否与轻度子宫内膜异位症相关。
比较22例患者与10名健康可育女性对照组的垂体 - 卵巢功能。
22例患有轻微或轻度子宫内膜异位症且其他方面原因不明的不孕症女性。
卵巢超声检查以及垂体和卵巢激素的放射免疫测定。
在82%的研究周期中发现了异常情况，包括未破裂卵泡黄素化、促黄体生成素（LH）峰宽以及黄体期孕酮浓度低。
在其他方面原因不明的不孕症女性中，垂体 - 卵巢功能障碍似乎与轻微或轻度子宫内膜异位症相关，但所显示的内分泌异常的多样性表明，子宫内膜异位症不太可能是其发病的病因。
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