Vargha-Khadem Faraneh, Gadian David G, Copp Andrew, Mishkin Mortimer
Institute of Child Health, University College London and Great Ormond Street Hospital for Children, 30 Guilford Street, London WC1N 1EH, UK.
Nat Rev Neurosci. 2005 Feb;6(2):131-8. doi: 10.1038/nrn1605.
That speech and language are innate capacities of the human brain has long been widely accepted, but only recently has an entry point into the genetic basis of these remarkable faculties been found. The discovery of a mutation in FOXP2 in a family with a speech and language disorder has enabled neuroscientists to trace the neural expression of this gene during embryological development, track the effects of this gene mutation on brain structure and function, and so begin to decipher that part of our neural inheritance that culminates in articulate speech.
长期以来，言语和语言是人类大脑的先天能力这一观点已被广泛接受，但直到最近才找到进入这些非凡能力的基因基础的切入点。在一个患有言语和语言障碍的家族中发现FOXP2基因的突变，使得神经科学家能够追踪该基因在胚胎发育过程中的神经表达，追踪这种基因突变对大脑结构和功能的影响，从而开始解读我们神经遗传中最终导致清晰言语的那部分内容。
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