Moussa M A A, Alsaeid M, Abdella N, Refai T M K, Al-Sheikh N, Gomez J E
Department of Community Medicine and Behavioural Sciences, Faculty of Medicine, Kuwait University, P.O. Box 24923, 13110 Safat, Kuwait.
Soc Sci Med. 2005 Apr;60(8):1835-44. doi: 10.1016/j.socscimed.2004.08.018.
Type 1 diabetes mellitus is a chronic disease that may have an impact on children's psychosocial adjustment. This study aimed to investigate the psychosocial characteristics of Kuwaiti children with type 1 diabetes as compared to healthy children without diabetes, and assess the impact of glycaemic control on psychosocial variables. A total of 349 school children aged 6-18 years with type 1 diabetes, and 409 children without diabetes having comparable age, gender, and social class were included in the study. Data were obtained by interviewing children and parents using a questionnaire. Psychological distress was measured by the Hopkins symptoms checklist-25 scale including anxiety and depression. Glycaemic control was assessed by glycosylated haemoglobin, HbA(IC) level. Glycaemic control was considered 'good to excellent' at HbA(IC)<8.0%, 'fair' at HbA(IC) 8.1 to 10.0%, and 'poor' at HbA(IC)>10.0%. Median scores of anxiety, depression, and total distress were significantly higher in children with diabetes indicating worse psychological adjustment. There was also significant difference between children with diabetes and those without diabetes in social aspects and school absence days. There was significant positive correlation between HbA(IC) concentration and scores of the psychological functioning indices. Children with poor glycaemic control had worse psychological adjustment. After controlling the variance accounted by gender and age, stepwise multiple regression analysis showed that girls, older children, children in need of emotional support, and those with higher HbA(IC) were at higher risk for psychological maladjustment. These variables explained 47.9% of the variation in total distress. In conclusion, the study supported our hypotheses. Children with diabetes had worse psychological adjustment, and distress was related to glycaemic control. Since psychological distress increases the risk for future complications due to its relation with glycaemic control, longitudinal studies are recommended to identify children with diabetes having distress at an early stage when preventive interventions are effective.
1型糖尿病是一种可能会对儿童心理社会适应产生影响的慢性疾病。本研究旨在调查科威特1型糖尿病儿童与无糖尿病健康儿童相比的心理社会特征,并评估血糖控制对心理社会变量的影响。该研究纳入了349名6至18岁的1型糖尿病学龄儿童以及409名年龄、性别和社会阶层与之匹配的无糖尿病儿童。通过使用问卷对儿童及其父母进行访谈来获取数据。心理困扰通过包含焦虑和抑郁的霍普金斯症状清单-25量表进行测量。血糖控制通过糖化血红蛋白HbA(IC)水平进行评估。当HbA(IC)<8.0%时,血糖控制被认为“良好至优秀”;当HbA(IC)为8.1至10.0%时,血糖控制被认为“中等”;当HbA(IC)>10.0%时,血糖控制被认为“差”。糖尿病儿童的焦虑、抑郁和总困扰的中位数得分显著更高,表明心理适应更差。糖尿病儿童与无糖尿病儿童在社会方面和缺课天数上也存在显著差异。HbA(IC)浓度与心理功能指标得分之间存在显著正相关。血糖控制差的儿童心理适应更差。在控制了性别和年龄所解释的方差后,逐步多元回归分析表明,女孩、年龄较大的儿童、需要情感支持的儿童以及HbA(IC)较高的儿童心理适应不良的风险更高。这些变量解释了总困扰中47.9%的变异。总之,该研究支持了我们的假设。糖尿病儿童心理适应更差,且困扰与血糖控制有关。由于心理困扰因其与血糖控制的关系而增加了未来并发症的风险,建议进行纵向研究以在预防性干预有效的早期阶段识别出有困扰的糖尿病儿童。