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1型糖尿病青少年的抑郁和焦虑症状——一项单中心观察性研究。

Depressive and anxiety symptoms in adolescents with type 1 diabetes - a single-centre observational study.

作者信息

Goncerz Dawid, Mazurek Edyta, Piasny Marta, Surówka Anna, B Starzyk Jerzy, Wójcik Małgorzata, Makara-Studzińska Marta

机构信息

Students' Scientific Group, Department of Paediatric and Adolescents Endocrinology, Chair of Paediatrics, Paediatric Institute, Jagiellonian University Medical College, Kraków, Poland.

Department of Statistics, Faculty of Economics and Finance, Wroclaw University of Economics and Business, Poland.

出版信息

Pediatr Endocrinol Diabetes Metab. 2023;29(4):231-236. doi: 10.5114/pedm.2023.133121.

Abstract

INTRODUCTION

Type 1 diabetes mellitus (T1DM) significantly affects the everyday functioning of the child and its family. This study aimed to assess the prevalence of symptoms of depression and anxiety and estimate their potential association with various clinical parameters.

MATERIAL AND METHODS

59 adolescents with T1DM (age 15-18) and their parents answered validated questionnaires (Children's Depression Inventory 2, The State-Trait Anxiety Inventory) and a survey assessing everyday functioning.

RESULTS

There were no significant differences in the occurrence of symptoms of depression in children and their parents (p = 0.975), but significant differences were found for anxiety. The distribution of the sten X1 and X2 values of adolescents and parents were different (p = 0.021 and p = 0.001, respectively). Girls were characterized by a higher level of depression both based on the overall score (p = 0.010) and the emotional problems (p = 0.022), and functional problems (p = 0.012). There was no significant correlation between diabetes duration time, glycaemic control, the occurrence of acute diabetes complications, and the parameters assessing anxiety and depression. Optimal glycaemic control, defined as HbA1c below 6.5% and TIR above 70%, was associated with sex (p = 0.001) and a high level of functional problems (p = 0.048).

CONCLUSIONS

In the studied population, adolescent girls with T1DM presented depressive symptoms more often than boys, and anxiety symptoms in adolescents were described more frequently by parents than by the teenagers themselves. Higher HbA1c was correlated with a higher level of functional problems.

摘要

引言

1型糖尿病(T1DM)严重影响儿童及其家庭的日常功能。本研究旨在评估抑郁和焦虑症状的患病率,并估计它们与各种临床参数之间的潜在关联。

材料与方法

59名患有T1DM的青少年(年龄15 - 18岁)及其父母回答了经过验证的问卷(儿童抑郁量表2、状态 - 特质焦虑量表)以及一项评估日常功能的调查。

结果

儿童及其父母抑郁症状的发生率无显著差异(p = 0.975),但焦虑症状存在显著差异。青少年和父母的X1和X2标准分分布不同(分别为p = 0.021和p = 0.001)。基于总分(p = 0.010)、情绪问题(p = 0.022)和功能问题(p = 0.012),女孩的抑郁水平更高。糖尿病病程、血糖控制、急性糖尿病并发症的发生与评估焦虑和抑郁的参数之间无显著相关性。将最佳血糖控制定义为糖化血红蛋白(HbA1c)低于6.5%且血糖在目标范围内时间(TIR)高于70%,其与性别(p = 0.001)和高水平的功能问题(p = 0.048)相关。

结论

在研究人群中,患有T1DM的青春期女孩比男孩更常出现抑郁症状,父母描述青少年焦虑症状的频率高于青少年自身。较高的HbA1c与较高水平的功能问题相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/214c/10826696/02fce20d3b3e/PEDM-29-51885-g001.jpg

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