Yuzawa Yohei, Kamimura Mikio, Nakagawa Hiroyuki, Kinoshita Tetsuya, Itoh Hidehiro, Takahashi Jun, Ebara Sohei
Department of Orthopaedic Surgery, Shinshu University School of Medicine, Aizawa Hospital, 2-5-1 Honjo, Matsumoto City, Nagano 390-8510, Japan.
J Spinal Disord Tech. 2005 Feb;18(1):23-8. doi: 10.1097/01.bsd.0000133494.70621.2e.
Nine patients with severely destructive spondyloarthropathy and marked neurologic deficits associated with dialysis-related amyloidosis underwent posterior decompression and fusion by means of instrumentation at our institute. All patients showed segmental kyphosis, six patients vertebral ankylosis, and eight patients spondylolisthesis. Spondylolisthesis at two levels was noted in three patients. Of the 11 levels of spondylolisthesis in all, 9 were proximally adjacent and 2 were distally adjacent to vertebral ankylosis. All patients underwent posterior decompression and multisegment fusion with autogenous iliac bone. From three to five spinal segments were fixed. Seven patients underwent posterior fusion by means of a pedicle or lateral mass screw between levels C3 and C7, one patient between C3 and C6, and one between C3 and T1. The clinical rate of improvement at the final follow-up was 74.3%. Though complete stability could not be achieved in three patients, the results were rated as good. No postoperative neurologic deterioration has been observed in this series, nor did any patients die immediately after surgery or during the postoperative follow-up period. As anterior long-span surgery might be too invasive for hemodialysis patients, we think that posterior decompression and fusion may well be a reasonable and effective strategy for severe hemodialysis-associated cervical spondyloarthropathy with neurologic deficits. To achieve complete stability, 360 degrees fusion with both anterior and posterior fixation with instrumentation may be required for these patients.
9例患有严重破坏性脊柱关节病且伴有与透析相关淀粉样变性相关的明显神经功能缺损的患者在我院接受了后路减压及器械辅助融合手术。所有患者均有节段性后凸,6例有椎体融合,8例有椎体滑脱。3例患者存在两个节段的椎体滑脱。在所有11个椎体滑脱节段中,9个位于椎体融合的近端相邻节段,2个位于远端相邻节段。所有患者均接受了后路减压及自体髂骨多节段融合手术。固定了3至5个脊柱节段。7例患者在C3至C7节段之间采用椎弓根或侧块螺钉进行后路融合,1例在C3至C6节段之间,1例在C3至T1节段之间。末次随访时临床改善率为74.3%。虽然3例患者未实现完全稳定,但结果评定为良好。本系列中未观察到术后神经功能恶化,也没有患者在术后立即死亡或在术后随访期间死亡。由于前路大跨度手术对血液透析患者的创伤可能过大,我们认为后路减压及融合对于伴有神经功能缺损的严重血液透析相关性颈椎病可能是一种合理有效的策略。对于这些患者,为实现完全稳定,可能需要前路和后路器械固定的360度融合。