Abumi K, Ito M, Kaneda K
Department of Orthopaedic Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Spine (Phila Pa 1976). 2000 Nov 15;25(22):2899-905. doi: 10.1097/00007632-200011150-00011.
Sixteen patients with hemodialysis-associated cervical spine disorders underwent surgical treatment. After analysis of the surgical results, the optimum surgical procedures for these disorders were discussed.
To evaluate the surgical results of cervical spine disorders associated with long-term hemodialysis and to propose the optimum surgical procedures for successful outcomes.
There have been few reports regarding surgical results of hemodialysis-related cervical spine disorders. Surgical treatment for this disorder is still challenging.
Sixteen patients with hemodialysis-associated cervical spine disorders were treated surgically. Duration of hemodialysis ranged from 8 to 27 years (average, 17 years). Before surgery, 14 patients showed severe cervical myelopathy, and the other 2 had radiculopathy in the upper extremities. Ten patients with marked destructive changes underwent circumferential reconstructive surgery involving pedicle screw fixation, anterior strut bone grafting, and posterior and/or anterior decompression. Two patients with cervical radiculopathy underwent posterior nerve root decompression by foraminotomy and fusion by pedicle screw fixation or spinous process wiring. The remaining four patients without spinal instability underwent posterior decompression by open-door laminoplasty.
Two patients died during follow-up. Follow-up periods in the surviving 14 patients ranged from 25 months to 92 months (average, 53 months). Marked neurologic recovery was obtained in all patients after surgery. Successful spinal fusion was obtained in all patients except one who underwent posterior fusion by spinous process wiring. Progressive destructive changes with significant instability at the adjacent mobile segments were observed in two patients who underwent circumferential fusion with a pedicle screw system more than 2 years after the initial surgery.
The pedicle screw system achieved a high fusion rate in reconstructive surgery of cervical destructive spondyloarthropathy, even in the presence of severe bone fragility.
16例患有血液透析相关性颈椎疾病的患者接受了手术治疗。在分析手术结果后,讨论了针对这些疾病的最佳手术方法。
评估与长期血液透析相关的颈椎疾病的手术效果,并提出获得成功结果的最佳手术方法。
关于血液透析相关性颈椎疾病手术结果的报道较少。针对这种疾病的手术治疗仍然具有挑战性。
对16例患有血液透析相关性颈椎疾病的患者进行了手术治疗。血液透析时间为8至27年(平均17年)。术前,14例患者表现为严重的颈髓病,另外2例有上肢神经根病。10例有明显破坏改变的患者接受了包括椎弓根螺钉固定、前路支撑植骨以及后路和/或前路减压的环形重建手术。2例患有颈椎神经根病的患者通过椎间孔切开术进行了后路神经根减压,并通过椎弓根螺钉固定或棘突钢丝进行了融合。其余4例无脊柱不稳的患者通过开门式椎板成形术进行了后路减压。
2例患者在随访期间死亡。其余14例存活患者的随访时间为25个月至92个月(平均53个月)。所有患者术后均有明显的神经功能恢复。除1例通过棘突钢丝进行后路融合的患者外,所有患者均成功实现了脊柱融合。在初次手术后2年以上接受椎弓根螺钉系统环形融合的2例患者中,观察到相邻活动节段出现进行性破坏改变并伴有明显不稳。
即使存在严重的骨质脆弱,椎弓根螺钉系统在颈椎破坏性脊椎关节病的重建手术中仍能实现较高的融合率。