Zacks David N, Johnson Mark W
The Retina Service, Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, Michigan 48105, USA.
Retina. 2005 Feb-Mar;25(2):135-40. doi: 10.1097/00006982-200502000-00003.
To present our results of intravitreal injection of triamcinolone acetonide (IVTA) combined with panretinal photocoagulation (PRP) for patients with concomitant clinically significant diabetic macular edema and proliferative diabetic retinopathy.
Charts of patients undergoing combined IVTA and PRP were reviewed. Outcome measures included visual acuity, presence of macular edema, and response of proliferative disease to laser photocoagulation.
Four patients were included in this study. All patients maintained stable visual acuity during the treatment period. All patients had improvement in the amount of macular edema, despite the application of PRP, as well as complete regression of their proliferative disease. There were no short-term complications associated with IVTA or PRP.
Combination treatment with IVTA and PRP may provide benefit in patients with diffuse diabetic macular edema who require urgent PRP for proliferative diabetic retinopathy by preventing exacerbation of macular edema.
介绍玻璃体内注射曲安奈德(IVTA)联合全视网膜光凝(PRP)治疗合并有临床显著性糖尿病黄斑水肿及增殖性糖尿病视网膜病变患者的结果。
回顾接受IVTA联合PRP治疗患者的病历。观察指标包括视力、黄斑水肿情况以及增殖性病变对激光光凝的反应。
本研究纳入4例患者。所有患者在治疗期间视力保持稳定。尽管进行了PRP治疗,但所有患者黄斑水肿量均有改善,其增殖性病变也完全消退。未出现与IVTA或PRP相关的短期并发症。
对于因增殖性糖尿病视网膜病变需要紧急进行PRP治疗的弥漫性糖尿病黄斑水肿患者,IVTA联合PRP治疗可能通过防止黄斑水肿加重而带来益处。