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一项针对接受高血压治疗一年以上的非裔美国人进行减压的随机对照试验。

A randomized controlled trial of stress reduction in African Americans treated for hypertension for over one year.

作者信息

Schneider Robert H, Alexander Charles N, Staggers Frank, Orme-Johnson David W, Rainforth Maxwell, Salerno John W, Sheppard William, Castillo-Richmond Amparo, Barnes Vernon A, Nidich Sanford I

机构信息

Institute for Natural Medicine and Prevention, Maharishi University of Management, Fairfield, Iowa, USA.

出版信息

Am J Hypertens. 2005 Jan;18(1):88-98. doi: 10.1016/j.amjhyper.2004.08.027.

Abstract

BACKGROUND

Psychosocial stress has been implicated in the disproportionately higher rates of hypertension among African Americans. This randomized controlled trial compared the effects of two stress reduction techniques and a health education control program on hypertension during a period of 1 year in African-American men and women (N = 150, mean age 49 +/- 10 years, mean blood pressure (BP) = 142/95 mm Hg) at an urban community health center.

METHODS

Interventions included 20 min twice a day of Transcendental Meditation (TM) or progressive muscle relaxation (PMR), or participation in conventional health education (HE) classes. All subjects continued usual medical care. Outcomes assessed were systolic BP and diastolic BP at 3, 6, 9, and 12 months after treatment, analyzed by repeated measures ANCOVA.

RESULTS

The TM group showed decreases in systolic BP/diastolic BP of -3.1/-5.7 mm Hg compared to -0.5/-2.9 mm Hg for PMR or HE, (P = .12 to .17 for systolic BP, P = .01 for diastolic BP). In addition the TM group demonstrated reduced use of antihypertensive medication relative to increases for PMR (P = .001) and HE (P = .09) groups. Group analysis by gender showed that women practicing TM had decreased BP (-7.3/-6.9 mm Hg) significantly more than women practicing PMR (0.7/-2.7 mm Hg) or HE (-.07/-3.0 mm Hg) (P .01 to .03). The change in men praticing TM (0.2 /-4.7 mm Hg) was greater than men practicing HE (-0.9/-2.0 mm Hg) for diastolic BP only (P = .09,) and not different from PMR men (-2.0/-3.1).

CONCLUSIONS

A selected stress reduction approach, the Transcendental Meditation program, may be useful as an adjunct in the long-term treatment of hypertension in African Americans.

摘要

背景

社会心理压力被认为是非裔美国人高血压发病率不成比例地较高的一个因素。这项随机对照试验比较了两种减压技术和一个健康教育对照项目对城市社区健康中心的非裔美国男性和女性(N = 150,平均年龄49±10岁,平均血压(BP)= 142/95 mmHg)在1年期间高血压的影响。

方法

干预措施包括每天两次20分钟的超觉静坐(TM)或渐进性肌肉松弛(PMR),或参加传统健康教育(HE)课程。所有受试者继续接受常规医疗护理。评估的结果是治疗后3、6、9和12个月时的收缩压和舒张压,通过重复测量协方差分析进行分析。

结果

与PMR或HE组的收缩压/舒张压下降-0.5/-2.9 mmHg相比,TM组的收缩压/舒张压下降了-3.1/-5.7 mmHg(收缩压P = 0.12至0.17,舒张压P = 0.01)。此外,与PMR组(P = 0.001)和HE组(P = 0.09)的增加相比,TM组的降压药物使用减少。按性别进行的组分析表明,进行TM的女性血压下降(-7.3/-6.9 mmHg)明显多于进行PMR的女性(0.7/-2.7 mmHg)或HE的女性(-0.07/-3.0 mmHg)(P = 0.01至0.03)。仅对于舒张压而言,进行TM的男性的变化(0.2 /-4.7 mmHg)大于进行HE的男性(-0.9/-2.0 mmHg)(P = 0.09),与进行PMR的男性(-2.0/-3.1)无差异。

结论

一种选定的减压方法,即超觉静坐项目,可能作为非裔美国人高血压长期治疗的辅助手段有用。

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