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一项全国队列研究中子宫切除或子宫内膜切除术后5年的再次入院情况。

Readmission to hospital 5 years after hysterectomy or endometrial resection in a national cohort study.

作者信息

Clarke A, Judge A, Herbert A, McPherson K, Bridgman S, Maresh M, Overton C, Altman D

机构信息

Public Health and Policy Research Unit, Barts and the London Queen Mary's School of Medicine and Dentistry, University of London, London, UK.

出版信息

Qual Saf Health Care. 2005 Feb;14(1):41-7. doi: 10.1136/qshc.2004.010926.

Abstract

OBJECTIVES

To investigate the readmission experience of a large national prospective cohort of women up to 5 years after undergoing either transcervical resection of the endometrium (TCRE) or hysterectomy to assess reasons for readmission and whether TCRE can be viewed as a definitive substitute for hysterectomy.

DESIGN AND PARTICIPANTS

Data are from the VALUE/MISTLETOE prospective national cohort studies of hysterectomy and TCRE respectively. 5294 women who underwent hysterectomy for dysfunctional uterine bleeding in 1994/5 and 4032 women who underwent TCRE in 1993/4 and who responded to postal questionnaires were included. Surgeons gathered operative details. Women completed postal follow up questionnaires at 3 and 5 years after surgery asking about readmission to hospital and reasons for readmission. Adjusted proportional hazard ratios were calculated for likelihood of readmission in each category comparing types of surgery.

RESULTS

41.7% of women undergoing hysterectomy and 44.6% of women undergoing TCRE experienced one or more readmissions to hospital overall within 5 years (adjusted hazard ratio for all readmissions (AHR) 0.87 (95% confidence interval (CI) 0.80 to 0.95)). 12.6% of hysterectomy patients and 30.3% of TCRE patients were readmitted for gynaecological reasons (AHR 0.40 (95% CI 0.33 to 0.48)). Rates of readmission for gynaecological reasons were similar up to 6 months but were markedly reduced for hysterectomy compared with TCRE patients towards the end of the follow up period (AHR for readmission at 3-5 years 0.28 (95% CI 0.20 to 0.39)).

CONCLUSIONS

There are differences in the pattern of readmission to hospital after hysterectomy and TCRE for dysfunctional uterine bleeding. Women undergoing a hysterectomy are less likely to be readmitted to hospital up to 5 years after their operation overall, and are significantly less likely to be readmitted for reasons related to their operation, particularly for gynaecological reasons. Hysterectomy appears to be a more definitive operation. The different options for surgery for dysfunctional uterine bleeding are not interchangeable; they represent different patterns of care. Information should be available to women and practitioners to inform choices between these options.

摘要

目的

调查一个大型全国性前瞻性队列中接受子宫内膜切除术(TCRE)或子宫切除术的女性长达5年的再次入院经历,以评估再次入院的原因,以及TCRE是否可被视为子宫切除术的确定性替代方案。

设计与参与者

数据分别来自VALUE/MISTLETOE关于子宫切除术和TCRE的全国性前瞻性队列研究。纳入了1994/1995年因功能失调性子宫出血接受子宫切除术的5294名女性,以及1993/1994年接受TCRE且回复邮寄问卷的4032名女性。外科医生收集手术细节。女性在术后3年和5年完成邮寄随访问卷,询问再次入院情况及再次入院原因。计算了比较手术类型的各类别再次入院可能性的调整比例风险比。

结果

总体而言,接受子宫切除术的女性中有41.7%,接受TCRE的女性中有44.6%在5年内经历了一次或多次再次入院(所有再次入院的调整风险比(AHR)为0.87(95%置信区间(CI)为0.80至0.95))。12.6%的子宫切除患者和30.3%的TCRE患者因妇科原因再次入院(AHR为0.40(95%CI为0.33至0.48))。在6个月内,因妇科原因的再次入院率相似,但在随访期结束时,与TCRE患者相比,子宫切除患者的再次入院率显著降低(3至5年再次入院的AHR为0.28(95%CI为0.20至0.39))。

结论

因功能失调性子宫出血接受子宫切除术和TCRE后,再次入院模式存在差异。总体而言,接受子宫切除术的女性在术后5年内再次入院的可能性较小,且因与手术相关原因再次入院的可能性显著较小,尤其是因妇科原因。子宫切除术似乎是一种更具确定性的手术。功能失调性子宫出血的不同手术选择不可互换;它们代表了不同的护理模式。应向女性和从业者提供信息,以帮助他们在这些选择之间做出决策。

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