Clarke A, Judge A, Herbert A, McPherson K, Bridgman S, Maresh M, Overton C, Altman D
Public Health and Policy Research Unit, Barts and the London Queen Mary's School of Medicine and Dentistry, University of London, London, UK.
Qual Saf Health Care. 2005 Feb;14(1):41-7. doi: 10.1136/qshc.2004.010926.
To investigate the readmission experience of a large national prospective cohort of women up to 5 years after undergoing either transcervical resection of the endometrium (TCRE) or hysterectomy to assess reasons for readmission and whether TCRE can be viewed as a definitive substitute for hysterectomy.
Data are from the VALUE/MISTLETOE prospective national cohort studies of hysterectomy and TCRE respectively. 5294 women who underwent hysterectomy for dysfunctional uterine bleeding in 1994/5 and 4032 women who underwent TCRE in 1993/4 and who responded to postal questionnaires were included. Surgeons gathered operative details. Women completed postal follow up questionnaires at 3 and 5 years after surgery asking about readmission to hospital and reasons for readmission. Adjusted proportional hazard ratios were calculated for likelihood of readmission in each category comparing types of surgery.
41.7% of women undergoing hysterectomy and 44.6% of women undergoing TCRE experienced one or more readmissions to hospital overall within 5 years (adjusted hazard ratio for all readmissions (AHR) 0.87 (95% confidence interval (CI) 0.80 to 0.95)). 12.6% of hysterectomy patients and 30.3% of TCRE patients were readmitted for gynaecological reasons (AHR 0.40 (95% CI 0.33 to 0.48)). Rates of readmission for gynaecological reasons were similar up to 6 months but were markedly reduced for hysterectomy compared with TCRE patients towards the end of the follow up period (AHR for readmission at 3-5 years 0.28 (95% CI 0.20 to 0.39)).
There are differences in the pattern of readmission to hospital after hysterectomy and TCRE for dysfunctional uterine bleeding. Women undergoing a hysterectomy are less likely to be readmitted to hospital up to 5 years after their operation overall, and are significantly less likely to be readmitted for reasons related to their operation, particularly for gynaecological reasons. Hysterectomy appears to be a more definitive operation. The different options for surgery for dysfunctional uterine bleeding are not interchangeable; they represent different patterns of care. Information should be available to women and practitioners to inform choices between these options.
调查一个大型全国性前瞻性队列中接受子宫内膜切除术(TCRE)或子宫切除术的女性长达5年的再次入院经历,以评估再次入院的原因,以及TCRE是否可被视为子宫切除术的确定性替代方案。
数据分别来自VALUE/MISTLETOE关于子宫切除术和TCRE的全国性前瞻性队列研究。纳入了1994/1995年因功能失调性子宫出血接受子宫切除术的5294名女性,以及1993/1994年接受TCRE且回复邮寄问卷的4032名女性。外科医生收集手术细节。女性在术后3年和5年完成邮寄随访问卷,询问再次入院情况及再次入院原因。计算了比较手术类型的各类别再次入院可能性的调整比例风险比。
总体而言,接受子宫切除术的女性中有41.7%,接受TCRE的女性中有44.6%在5年内经历了一次或多次再次入院(所有再次入院的调整风险比(AHR)为0.87(95%置信区间(CI)为0.80至0.95))。12.6%的子宫切除患者和30.3%的TCRE患者因妇科原因再次入院(AHR为0.40(95%CI为0.33至0.48))。在6个月内,因妇科原因的再次入院率相似,但在随访期结束时,与TCRE患者相比,子宫切除患者的再次入院率显著降低(3至5年再次入院的AHR为0.28(95%CI为0.20至0.39))。
因功能失调性子宫出血接受子宫切除术和TCRE后,再次入院模式存在差异。总体而言,接受子宫切除术的女性在术后5年内再次入院的可能性较小,且因与手术相关原因再次入院的可能性显著较小,尤其是因妇科原因。子宫切除术似乎是一种更具确定性的手术。功能失调性子宫出血的不同手术选择不可互换;它们代表了不同的护理模式。应向女性和从业者提供信息,以帮助他们在这些选择之间做出决策。