强直性脊柱炎患者中骨桥与椎体骨密度的关系。
The association of syndesmophytes with vertebral bone mineral density in patients with ankylosing spondylitis.
作者信息
Gilgil Erdal, Kaçar Cahit, Tuncer Tiraje, Bütün Bülent
机构信息
Division of Rheumatology, Faculty of Medicine, Akdeniz University, Antalya, Turkey.
出版信息
J Rheumatol. 2005 Feb;32(2):292-4.
OBJECTIVE
To determine bone mineral density (BMD) using the posteroanterior L2-L4 (PA) and lateral L3 (LAT-L3) projections of dual energy x-ray absorptiometry (DEXA) in patients with ankylosing spondylitis (AS), and to evaluate the relationship between BMD and the presence of syndesmophytes.
METHODS
Twenty men with AS were studied. BMD was measured by femoral neck DEXA, PA DEXA, and LAT-L3 DEXA scans. Radiographs of lumbar spine were evaluated to obtain a lumbar spine score (LSS) for the presence of syndesmophytes. Twenty-three age matched healthy men served as controls.
RESULTS
While there was no significant difference in BMD from PA DEXA results between AS patients and controls, BMD from the LAT-L3 DEXA was significantly reduced in AS patients (p = 0.009). LSS correlated significantly with BMD from PA DEXA (r = 0.55, p = 0.013), but not with BMD of LAT-L3 DEXA.
CONCLUSION
LAT-L3 DEXA was superior to PA DEXA in detecting a decrease of BMD in patients with AS. The presence of syndesmophytes had no distorting effect on BMD measured by LAT-L3 DEXA.
目的
采用双能X线吸收法（DEXA）的后前位L2-L4（PA）和侧位L3（LAT-L3）投照来测定强直性脊柱炎（AS）患者的骨密度（BMD），并评估BMD与骨桥形成之间的关系。
方法
对20例男性AS患者进行研究。通过股骨颈DEXA、PA DEXA和LAT-L3 DEXA扫描测量BMD。评估腰椎X线片以获得骨桥形成的腰椎评分（LSS）。23名年龄匹配的健康男性作为对照。
结果
虽然AS患者和对照组之间PA DEXA结果的BMD无显著差异，但AS患者LAT-L3 DEXA的BMD显著降低（p = 0.009）。LSS与PA DEXA的BMD显著相关（r = 0.55，p = 0.013），但与LAT-L3 DEXA的BMD无关。
结论
LAT-L3 DEXA在检测AS患者BMD降低方面优于PA DEXA。骨桥的存在对LAT-L3 DEXA测量的BMD没有干扰作用。
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