Weisskoff R M, Kiihne S
Massachusetts General Hospital, Department of Radiology, Charlestown 02129.
Magn Reson Med. 1992 Apr;24(2):375-83. doi: 10.1002/mrm.1910240219.
We present a novel NMR imaging technique that allows absolute determination of the magnetic susceptibility constant, chi, of a solution. By comparing the phase difference of MR images produced with an instant (echo planar) "offset" spin-echo sequence, we obtain a direct measure of the magnetic field perturbations caused by the solution. We demonstrate this method with Gd(DTPA), Dy(DTPA), human red blood cells, and superparamagnetic iron oxide particles.
我们提出了一种新颖的核磁共振成像技术，该技术能够绝对测定溶液的磁化率常数χ。通过比较使用即时（回波平面）“偏移”自旋回波序列生成的磁共振图像的相位差，我们获得了由溶液引起的磁场扰动的直接测量值。我们用钆（二乙三胺五乙酸）、镝（二乙三胺五乙酸）、人类红细胞和超顺磁性氧化铁颗粒演示了这种方法。
