Necrolytic migratory erythema without glucagonoma associated with hepatitis B.

We report a case of necrolytic migratory erythema (NME) without glucagonoma associated with hepatitis B. Although the most common cause of NME is a glucagon-secreting alpha-islet cell tumor of the pancreas, a dermatitis clinically and histologicaly identical to NME has been described in patients without glucagonoma. Impairment of hepatic dysfunction has been identified in the majority of them. However, NME associated with hepatitis B has never been reported in the literature. NME belongs to the family of necrolytic erythemas that share similar clinical and histologic findings. The terms used to describe NME and related conditions in the medical literature are confused. We added some discussion on the terminology of this disease.