Huiskamp E A, Müskens R P H M, Ballast A, Hooymans J M M
Department of Ophthalmology, University Hospital Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
Graefes Arch Clin Exp Ophthalmol. 2005 Jul;243(7):727-30. doi: 10.1007/s00417-004-1102-9. Epub 2005 Feb 9.
To report the treatment outcome of photodynamic therapy with verteporfin (PDT) for exudative retinal detachment associated with diffuse choroidal haemangioma in Sturge-Weber syndrome.
An interventional case report of a 12-year-old girl with Sturge-Weber syndrome who developed an exudative retinal detachment (visual acuity 20/400) that was treated with PDT under general anaesthesia. PDT was performed according to the standard (macular degeneration) protocol, using three nonoverlapping spots of 4,000 microm.
Subretinal fluid resolved completely over a period of 5 months and visual acuity increased to 20/50. No side effects of the PDT treatment were encountered during 9 months' follow-up.
In our patient PDT with verteporfin effectively resolved the exudative retinal detachment associated with a diffuse choroidal haemangioma. Resolution of subretinal fluid occurred over several months without retreatment. We noted no side effects of the combination PDT and general anaesthesia, nor did we encounter ocular side effects of the treatment.
报告维替泊芬光动力疗法（PDT）治疗斯特奇-韦伯综合征伴弥漫性脉络膜血管瘤所致渗出性视网膜脱离的治疗效果。
对一名12岁患斯特奇-韦伯综合征的女孩进行介入性病例报告，该女孩发生渗出性视网膜脱离（视力20/400），在全身麻醉下接受了PDT治疗。PDT按照标准（黄斑变性）方案进行，使用三个不重叠的4000微米光斑。
视网膜下液在5个月内完全消退，视力提高到20/50。在9个月的随访期间未出现PDT治疗的副作用。
在我们的患者中，维替泊芬PDT有效解决了与弥漫性脉络膜血管瘤相关的渗出性视网膜脱离。视网膜下液在数月内消退，无需再次治疗。我们未发现PDT与全身麻醉联合使用的副作用，也未遇到该治疗的眼部副作用。
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