North Carol S, Pfefferbaum Betty, Tivis Laura, Kawasaki Aya, Reddy Chandrashekar, Spitznagel Edward L
Washington University School of Medicine, Department of Psychiatry, St. Louis, MO 63110, USA.
Ann Clin Psychiatry. 2004 Oct-Dec;16(4):209-15. doi: 10.1080/10401230490522034.
The course of posttraumatic stress disorder (PTSD) in populations directly exposed to terrorist attacks is of major importance in the post-9/11 era. Because no systematic diagnostic studies of the most highly exposed individuals of the 9/11 terrorist attacks have yet been done, the Oklahoma City bombing remains a unique opportunity to examine PTSD over time in high-exposure terrorist victims.
This study assessed 137 survivors in the direct path of the explosion at approximately 6 and 17 months postdisaster, using the Diagnostic Interview Schedule.
Combined index and follow-up data yielded a higher (41%) incidence of PTSD than detected at index (32%) or follow-up (31%). All PTSD was chronic (89% unremitted at 17 months) with no delayed-onset cases. The avoidance and numbing symptom group C, unlike groups B and D alone, was pivotal to current PTSD status and was associated with indicators of functioning at index and follow-up. The findings at index were sustainable.
This follow-up study confirmed the immediacy of onset of PTSD and its persistence over time, pointing to the need for early interventions that continue over the long term. Group C avoidance and numbing symptoms may aid in early recognition of PTSD and in predicting long-term functioning.
在9·11事件后的时代,直接遭受恐怖袭击人群中的创伤后应激障碍(PTSD)病程至关重要。由于尚未对9·11恐怖袭击中暴露程度最高的个体进行系统的诊断研究,俄克拉何马城爆炸案仍是一个独特的机会,可用于长期研究高暴露恐怖袭击受害者的创伤后应激障碍。
本研究在灾难发生后约6个月和17个月时,使用诊断访谈表对爆炸直接影响范围内的137名幸存者进行了评估。
综合索引数据和随访数据得出的创伤后应激障碍发病率(41%)高于索引时(32%)或随访时(31%)检测到的发病率。所有创伤后应激障碍均为慢性(17个月时89%未缓解),无延迟发作病例。与单独的B组和D组不同,回避和麻木症状C组对当前创伤后应激障碍状态至关重要,并且与索引时和随访时的功能指标相关。索引时的研究结果具有可持续性。
这项随访研究证实了创伤后应激障碍发病的即时性及其随时间的持续性,表明需要进行长期持续的早期干预。C组的回避和麻木症状可能有助于早期识别创伤后应激障碍并预测长期功能。