Aguayo Víctor M, Koné Diakalia, Bamba Sory Ibrahim, Diallo Baba, Sidibé Yacouba, Traoré Diakalia, Signé Pierre, Baker Shawn K
UNICEF Regional Office for West and Central Africa, Dakar-Yoff, Senegal.
Public Health Nutr. 2005 Feb;8(1):33-7. doi: 10.1079/phn2005665.
In Mali, an estimated 73% of pregnant women are anaemic largely due to iron deficiency. National policy recommends women to take iron and folic acid supplements daily from first prenatal contact until 3 months postpartum. However, many pregnant women in Mali could benefit from multiple micronutrient supplements.
To assess pregnant women's acceptability of and adherence to a daily multiple micronutrient supplementation scheme compared with the current daily iron and folic acid supplementation scheme.
Seventy pregnant women were allocated to either the daily multiple micronutrient or daily iron and folic acid supplementation scheme. Women started receiving supplements at the end of the first trimester of pregnancy until delivery and throughout the first 3 months postpartum.
No significant differences were observed between comparison groups with respect to women's perceptions about supplement size, colour, taste or flavour. Adherence to the multiple micronutrient supplementation scheme was better (257.5+/-20.9 tablets; average adherence 95.4%) than that to the iron and folic acid supplementation scheme (238.5+/-32.7 tablets; average adherence 92.2%; P=0.008) although both were very good, as were women's perceptions about the benefits of micronutrient supplements to their health and that of their newborns.
Malian women adhere to prenatal/postpartum micronutrient supplementation - no matter what supplement is chosen - when access to supplements is guaranteed and when they are provided with minimum, consistent and easily understandable information and counselling, indicating that these are key elements to ensure effective programmes. These findings, together with those of the global research agenda on the efficacy of multiple micronutrient supplements for pregnant women, will inform policy development in Mali for the effective control of iron deficiency and iron-deficiency anaemia in pregnant women.
在马里，估计73%的孕妇贫血，主要原因是缺铁。国家政策建议女性从首次产前检查直至产后3个月每天补充铁和叶酸。然而，马里的许多孕妇可以从多种微量营养素补充剂中获益。
评估与当前每日补充铁和叶酸的方案相比，孕妇对每日补充多种微量营养素方案的接受度和依从性。
70名孕妇被分配到每日补充多种微量营养素或每日补充铁和叶酸的方案中。女性从妊娠中期末开始接受补充剂，直至分娩，并在产后的前3个月持续服用。
在女性对补充剂大小、颜色、味道或风味的看法方面，比较组之间未观察到显著差异。尽管两种方案的依从性都很好，且女性对微量营养素补充剂对自身及新生儿健康益处的看法也都很好，但补充多种微量营养素方案的依从性（257.5±20.9片；平均依从率95.4%）优于补充铁和叶酸的方案（238.5±32.7片；平均依从率92.2%；P=0.008）。
当能够保证补充剂的供应，并为马里女性提供最少、一致且易于理解的信息和咨询时，她们会坚持产前/产后微量营养素补充——无论选择何种补充剂，这表明这些是确保有效方案的关键要素。这些发现，连同全球关于孕妇补充多种微量营养素功效的研究议程的结果，将为马里制定有效控制孕妇缺铁和缺铁性贫血的政策提供参考。
