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人类BOULE基因突变并非精子发生受损的主要原因。

Mutations in the human BOULE gene are not a major cause of impaired spermatogenesis.

作者信息

Westerveld G Henrike, Repping Sjoerd, Leschot Nico J, van der Veen Fulco, Lombardi M Paola

机构信息

Center for Reproductive Medicine, Department of Obstetrics and Gynaecology, Academic Medical Center, Meibergdreef 9, H4-205, 1105 AZ Amsterdam, The Netherlands.

出版信息

Fertil Steril. 2005 Feb;83(2):513-5. doi: 10.1016/j.fertnstert.2004.10.013.

DOI:10.1016/j.fertnstert.2004.10.013
PMID:15705409
Abstract

Mutation screening of the BOULE gene in 156 men with azoospermia or severe oligozoospermia revealed no relevant mutations; thus, mutations in BOULE can be eliminated as a major cause of impaired spermatogenesis.

摘要

对156名无精子症或严重少精子症男性的BOULE基因进行突变筛查，未发现相关突变；因此，可排除BOULE基因突变是精子发生受损的主要原因。

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