Attout H, Martre A, Guez S, Series C
Service de médecine interne, CHU Pellegrin, 33000 Bordeaux, France.
Rev Med Interne. 2005 Feb;26(2):141-4. doi: 10.1016/j.revmed.2004.09.021.
Primary Sjogren syndrome is considered as the most frequent connective tissue disease. Neurological complications may affect the peripheral nervous system and to lesser extent the central nervous system. Autonomic system nervous dysfunction and epilepsy have been rarely reported.
We present on case of Sjogren's syndrome with epilepsy and autonomic nervous system dysfunction. The epilepsia respond to valproate.
Autoimmune investigations for Sjogren's syndrome should be initiated in any patient presenting with unexplained neurologic manifestations.
原发性干燥综合征被认为是最常见的结缔组织病。神经并发症可能影响周围神经系统,对中枢神经系统的影响较小。自主神经系统功能障碍和癫痫很少有报道。
我们报告一例患有癫痫和自主神经系统功能障碍的干燥综合征病例。癫痫对丙戊酸盐有反应。
对于任何出现不明原因神经表现的患者,都应启动针对干燥综合征的自身免疫检查。