Andonopoulos A P, Ballas C
Department of Medicine, University of Patras School of Medicine, Greece.
Rheumatol Int. 1995;15(3):127-9. doi: 10.1007/BF00302131.
The case of a 65-year-old female with primary Sjögren's syndrome and severe autonomic cardiovascular neuropathy, manifested by incapacitating postural hypotension, is presented. It is postulated that the patient's Sjögren's syndrome was responsible for the autonomic neuropathy, probably via a vasculitic mechanism. Treatment with hydrocortisone resulted in improvement in the patient's symptoms but it did not significantly alter the objective findings of autonomic dysfunction. We suggest that it is probably worth studying Sjögren's patients for evidence of autonomic neuropathy.
本文报告了一例65岁女性原发性干燥综合征患者,伴有严重的自主神经心血管神经病变,表现为严重的体位性低血压。据推测,患者的干燥综合征可能通过血管炎机制导致了自主神经病变。氢化可的松治疗使患者症状有所改善,但并未显著改变自主神经功能障碍的客观检查结果。我们建议,对干燥综合征患者进行自主神经病变证据的研究可能是值得的。