Ridley J, Hoey K, Ballagh-Howes N
London Health Sciences Centre, Ontario.
CANNT J. 1999 Summer;9(3):20-6.
Dialysis saves lives. However, dialysis alone cannot make those lives active and meaningful. Exercise, in particular, is critical in the rehabilitation of many individuals with chronic renal insufficiency The purpose of this pilot study was to: 1) examine changes in participants' physical capacity and quality of life with the intervention of a 12-week exercise program; 2) investigate whether erythropoietin (EPO) and antihypertensive medication dosages were reduced in the participants; 3) examine the feasibility of incorporating exercise into the London Health Sciences Centre (LHSC) hemodialysis program. A quasi-experimental one-group pre- and post-test design was utilized. Eight subjects completed the 12-week study. The exercise program involved a warm-up, stretching, strengthening, and cardiovascular training. The results demonstrated improvements in the participants'physical capacity, quality of life, and ability to perform activities of daily living (ADLs). There were no discernable trends in the participants' hemoglobin levels or EPO dosages. Although there were no statistically significant changes in participants' blood pressures, five out of the six participants who began the program on antihypertensive medications either had the dosages decreased or the drug(s) discontinued. Data from this small prospective study supports previous research that an exercise during dialysis program is safe and has the potential to result in positive patient outcomes.
透析能挽救生命。然而，仅靠透析并不能让这些生命充满活力且有意义。特别是运动，对于许多慢性肾功能不全患者的康复至关重要。这项初步研究的目的是：1）通过一项为期12周的运动计划干预，检查参与者身体能力和生活质量的变化；2）调查参与者的促红细胞生成素（EPO）和抗高血压药物剂量是否减少；3）检验将运动纳入伦敦健康科学中心（LHSC）血液透析项目的可行性。采用了准实验性单组前后测设计。八名受试者完成了为期12周的研究。运动计划包括热身、伸展、强化和心血管训练。结果表明，参与者的身体能力、生活质量以及进行日常生活活动（ADL）的能力都有所改善。参与者的血红蛋白水平或EPO剂量没有明显趋势。尽管参与者的血压没有统计学上的显著变化，但开始该计划时服用抗高血压药物的六名参与者中有五人的药物剂量减少或停药。这项小型前瞻性研究的数据支持了先前的研究，即透析期间进行运动计划是安全的，并且有可能为患者带来积极的结果。
