Smith C A, Boyer M, Raby E
Ottawa Hospital, Ontario.
CANNT J. 1999 Summer;9(3):28-32; quiz 33-4.
The advent of night-time exchange devices (NXDs), such as the Quantum, gives the client on home peritoneal dialysis the option of five exchanges well spaced in a day or, for those who need only four exchanges a day, the ability to change their long dwell to the daytime.
To ascertain whether we were able to attain the NKF-DOQI recommended Kt/V of 2.0 for CAPD clients by adding a fifth exchange utilizing the Quantum NXD or by introducing a long daytime dwell for clients who only needed four exchanges per day. We also looked at alternative uses for a NXD.
As part of our CQI process for all clients on home peritoneal dialysis, dialysis adequacy testing is performed two weeks after the start of full prescription and biannually thereafter. In this study, the first group of clients, the "lifestyle group", changed to using the NXD to allow more daytime freedom. This first group had repeated 24 hour dialysate collections to ensure they maintained adequate Kt/Vs. The second group of clients, the "adequacy group", had Kt/Vs falling below the NKF-DOQI recommendation of 2.0. This second group had their peritoneal dialysis prescription optimized utilizing a computer modeling program. Their prescription was then changed accordingly Two weeks after the change in prescription, 24 hour dialysate collections were repeated for each client to ensure the new Kt/Vs were within the predicted parameters.
We were able to attain the NKF-DOQI recommended Kt/V, utilizing the CANUSA recommended fill volumes, for all clients underdialyzed on CAPD through the addition of a fifth exchange using the NXD. Other clients who may benefit from the use of NXDs are those who need more daytime freedom.
诸如量子夜间交换装置(NXDs)的出现,为居家腹膜透析患者提供了两种选择,一是每天进行五次间隔合理的交换,二是对于那些每天只需进行四次交换的患者,能够将长时间留腹改为日间留腹。
通过使用量子夜间交换装置增加第五次交换,或为每日只需四次交换的患者引入长时间日间留腹,来确定我们是否能够使持续性非卧床腹膜透析(CAPD)患者达到美国国家肾脏基金会(NKF)-透析结果质量倡议(DOQI)推荐的2.0的Kt/V值。我们还研究了夜间交换装置的其他用途。
作为我们对所有居家腹膜透析患者的持续质量改进(CQI)过程的一部分,在开始全剂量处方两周后进行透析充分性测试,此后每半年进行一次。在本研究中,第一组患者,即“生活方式组”,改用夜间交换装置以获得更多日间自由。该第一组患者多次进行24小时透析液收集,以确保他们维持足够的Kt/V值。第二组患者,即“充分性组”,其Kt/V值低于NKF-DOQI推荐的2.0。该第二组患者利用计算机建模程序优化其腹膜透析处方。然后相应地更改他们的处方。在处方更改两周后,为每位患者再次进行24小时透析液收集,以确保新的Kt/V值在预测参数范围内。
通过使用夜间交换装置增加第五次交换,我们能够利用加拿大-美国(CANUSA)推荐的填充量,使所有CAPD透析不充分的患者达到NKF-DOQI推荐的Kt/V值。其他可能从使用夜间交换装置中受益的患者是那些需要更多日间自由的患者。