Aoyagi Masaru
Department of Otolaryngology, Head and Neck Surgery, Course of Biological Structure and Cognitive Integration Science, Yamagata University School of Medicine, Yamagata.
Nihon Jibiinkoka Gakkai Kaiho. 2005 Jan;108(1):1-7. doi: 10.3950/jibiinkoka.108.1.
The important factors in the prognostic diagnosis of acute peripheral facial palsy are (1) the causal disease, (2) the site of injury and (3) the degree of injury, although the age of the patient, complication, treatment method and initial day of treatment are also important. Among these 3 factors, the degree of injury is most strongly related to the prognosis. However, the diagnosis of etiology is the most important for the selection of the treatment method. Above all, the differential diagnosis between Bell's palsy and zoster sine herpete (Ramsay Hunt syndrome), is the most significant. However, it is impossible to diagnose all patients with complete accuracy within 3 days after the onset of palsy, even using molecular biological examination including polymerase chain reaction analysis. The diagnosis of the site of injury does not contribute to the prediction of prognosis or the selection of treatment method, except for the determination of the approaching route of the facial nerve decompression for traumatic facial palsy. The scoring system of facial movement (40-point method), nerve excitability test (NET), electroneurography (ENoG), transcranial magnetic stimulation (TMS) and stapedial reflex (SR) are commonly used to estimate the degree of injury. To estimate the accuracy of these examinations, sensitivity and specificity of the tests were calculated according to the findings within 3 days after the onset of palsy and the outcome of 116 patients with Bell's palsy and 31 with Ramsay Hunt syndrome. According to the results, none of these tests seem to be a perfect diagnostic examination for the completely precise prediction of prognosis. However, a patient is predicted to have a good prognosis, if the following 3 findings are observed: (1) more than 10 points in the 40-point scoring system of facial movement, (2) a positive response to TMS and (3) a positive response to SR. An antidromic facial nerve response probably contributes to a precise prediction of prognosis within 3 days after the onset of facial palsy.
(1)病因疾病;(2)损伤部位;(3)损伤程度,不过患者年龄、并发症、治疗方法及治疗起始日也很重要。在这三个因素中,损伤程度与预后的相关性最强。然而,病因诊断对于治疗方法的选择最为重要。首要的是,贝尔面瘫与无疱疹性带状疱疹(拉姆齐·亨特综合征)之间的鉴别诊断最为关键。然而,即便使用包括聚合酶链反应分析在内的分子生物学检查,也无法在面瘫发病后3天内对所有患者进行完全准确的诊断。除了确定外伤性面瘫面神经减压的进路外,损伤部位的诊断对预后预测或治疗方法的选择并无帮助。面部运动评分系统(40分法)、神经兴奋性测试(NET)、神经电图(ENoG)、经颅磁刺激(TMS)及镫骨肌反射(SR)常用于评估损伤程度。为评估这些检查的准确性,根据面瘫发病后3天内的检查结果以及116例贝尔面瘫患者和31例拉姆齐·亨特综合征患者的预后情况,计算了各项检查的敏感性和特异性。根据结果,这些检查似乎都不是能完全精确预测预后的完美诊断方法。然而,如果出现以下三个表现,则预测患者预后良好:(1)面部运动40分评分系统中得分超过10分;(2)对TMS有阳性反应;(3)对SR有阳性反应。逆行性面神经反应可能有助于在面瘫发病后3天内精确预测预后。