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新药上市对寿命的影响:来自1982年至2001年52个国家纵向疾病层面数据的证据。

The impact of new drug launches on longevity: evidence from longitudinal, disease-level data from 52 countries, 1982-2001.

作者信息

Lichtenberg Frank R

机构信息

Graduate School of Business, Columbia University, National Bureau of Economic Research, 614 Uris Hall, 3022 Broadway, New York, NY 10027, USA.

出版信息

Int J Health Care Finance Econ. 2005 Mar;5(1):47-73. doi: 10.1007/s10754-005-6601-7.

DOI:10.1007/s10754-005-6601-7
PMID:15714263
Abstract

We perform an econometric analysis of the effect of new drug launches on longevity, using data from the IMS Health Drug Launches database and the WHO Mortality Database. Under conservative assumptions, our estimates imply that the average annual increase in life expectancy of the entire population resulting from new drug launches is about one week, and that the incremental cost effectiveness ratio (new drug expenditure per person per year divided by the increase in life-years per person per year attributable to new drug launches) is about $6750--far lower than most estimates of the value of a statistical life-year.

摘要

我们利用艾美仕市场研究公司(IMS Health)药品上市数据库和世界卫生组织(WHO)死亡率数据库的数据,对新药上市对寿命的影响进行了计量经济学分析。在保守假设下,我们的估计表明,新药上市使整个人口预期寿命的年平均增加约为一周,增量成本效益比(每人每年的新药支出除以新药上市导致的每人每年生命年数的增加)约为6750美元,远低于大多数统计生命年价值的估计。

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本文引用的文献

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Health Econ. 2005 Mar;14(3):269-92. doi: 10.1002/hec.931.
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Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone.在尤因肉瘤和骨原始神经外胚层肿瘤的标准化疗中添加异环磷酰胺和依托泊苷。
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Cureus. 2023 Mar 30;15(3):e36899. doi: 10.7759/cureus.36899. eCollection 2023 Mar.
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Public-private partnership alternative for a national pharmacare program in Canada.加拿大国家药物保险计划的公私合作替代方案。
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Changes in launch delay and availability of pharmaceuticals in 30 European markets over the past two decades.过去二十年中,30 个欧洲市场的药品上市延迟和可及性的变化。
BMC Health Serv Res. 2022 Nov 30;22(1):1457. doi: 10.1186/s12913-022-08866-7.
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Does health technology assessment compromise access to pharmaceuticals?卫生技术评估是否会影响药品的可及性?
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Multidisciplinary academic perspectives during the COVID-19 pandemic.新冠疫情期间的多学科学术视角。
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