Anstey N M, Currie B J, Withnall K M
Department of Medicine, Royal Darwin Hospital, Casuarina, Australia.
Clin Infect Dis. 1992 Jan;14(1):83-91. doi: 10.1093/clinids/14.1.83.
Eleven cases of blood culture-positive, community-acquired pneumonia due to the human commensal Acinetobacter baumannii were studied in Darwin in the Northern Territory of Australia during the 10-year period from March 1981 through February 1991. Demographic risk factors included male gender, age of greater than 45 years, and Aboriginal ethnic background. Multiple clinical risk factors, including cigarette smoking, alcoholism, chronic obstructive airway disease, and diabetes mellitus, were noted in all cases and contributed to the high mortality (64%). In all cases pneumonia was clinically fulminant. A fatal outcome was strongly associated with inappropriate initial antibiotic therapy. All tested isolates of Acinetobacter were sensitive to gentamicin and resistant to cefotaxime. The 34 previously reported cases of community-acquired acinetobacter pneumonia are reviewed, and appropriate therapeutic regimens are identified.
1981年3月至1991年2月的10年间，在澳大利亚北领地达尔文市对11例血培养阳性、由人体共生菌鲍曼不动杆菌引起的社区获得性肺炎病例进行了研究。人口统计学风险因素包括男性、年龄大于45岁以及原住民种族背景。所有病例均存在多种临床风险因素，包括吸烟、酗酒、慢性阻塞性气道疾病和糖尿病，这些因素导致了高死亡率（64%）。所有病例的肺炎在临床上均呈暴发性。死亡结局与初始抗生素治疗不当密切相关。所有检测的不动杆菌分离株对庆大霉素敏感，对头孢噻肟耐药。对先前报道的34例社区获得性不动杆菌肺炎病例进行了综述，并确定了适当的治疗方案。
