Okazaki S, Sako K, Yonemasu Y
Department of Neurosurgery, Asahikawa Medical College, Japan.
Brain Res. 1992 Mar 20;575(2):347-50. doi: 10.1016/0006-8993(92)90103-g.
Neuropeptide Y (NPY) was continuously administered to Wistar rats intracarotidly via the external carotid artery and local cerebral blood flow (LCBF) was measured by a quantitative autoradiography using [14C]iodoantipyrine. A remarkable reduction in LCBF was observed in the NPY infused hemisphere. This depression was irregular and was particularly evident in the hippocampus, selective thalamic nuclei and the cerebral cortex.