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Effects of intracarotid infusion of neuropeptide Y on cerebral blood flow in rats.

作者信息

Okazaki S, Sako K, Yonemasu Y

机构信息

Department of Neurosurgery, Asahikawa Medical College, Japan.

出版信息

Brain Res. 1992 Mar 20;575(2):347-50. doi: 10.1016/0006-8993(92)90103-g.

DOI:10.1016/0006-8993(92)90103-g
PMID:1571793
Abstract

Neuropeptide Y (NPY) was continuously administered to Wistar rats intracarotidly via the external carotid artery and local cerebral blood flow (LCBF) was measured by a quantitative autoradiography using [14C]iodoantipyrine. A remarkable reduction in LCBF was observed in the NPY infused hemisphere. This depression was irregular and was particularly evident in the hippocampus, selective thalamic nuclei and the cerebral cortex.

摘要

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