Ciriza de los Ríos C, García Menéndez L, Díez Hernández A, Fernández Eroles A L, Vega Fernández A, Enguix Armada A
Laboratorio de Motilidad, Servicio de Aparato Digestivo, Hospital del Bierzo, León, Spain.
J Clin Gastroenterol. 2005 Mar;39(3):220-3. doi: 10.1097/01.mcg.0000152780.76524.a9.
Esophageal motility abnormalities have been observed in patients with gastroesophageal reflux disease.
The aim of the present study was to determine if esophageal motor disorders in patients with a positive response to the omeprazole test are related to the existence of reflux or they are concomitant findings.
A 24-hour pH monitoring and a stationary manometry were performed on 128 patients: 49 of them had normal manometry, 31 hypotensive lower esophageal sphincter, 29 motor disorder in esophageal body, and 19 hypotensive lower esophageal sphincter and motor disorder in esophageal body.
We found an association between the presence of abnormal reflux and motor disorder in esophageal body (chi test; P < 0.05). However, ineffective esophageal motility was the disorder most strongly related to reflux, whereas the hypercontractile disorders were not clearly attributed to it.
Esophageal manometric abnormalities should be considered cautiously before considering a motor disorder as a consequence of abnormal reflux.
胃食管反流病患者中已观察到食管动力异常。
本研究的目的是确定对奥美拉唑试验有阳性反应的患者的食管运动障碍是否与反流的存在有关，或者它们是伴随出现的发现。
对128例患者进行了24小时pH监测和静态测压：其中49例测压正常，31例食管下括约肌压力降低，29例食管体部运动障碍，19例食管下括约肌压力降低且食管体部运动障碍。
我们发现食管体部异常反流与运动障碍之间存在关联（卡方检验；P < 0.05）。然而，无效食管动力是与反流最密切相关的障碍，而高收缩性障碍与反流的关系并不明确。
在将运动障碍视为异常反流的后果之前，应谨慎考虑食管测压异常。
