Lin Chen-Sung, Hsu Han-Shui, Tsai Chien-Ho, Li Wing-Yin, Huang Min-Hsiung
Taipei Veterans General Hospital, Taiwan.
J Chin Med Assoc. 2004 Nov;67(11):583-6.
Gastrointestinal mesenchymal tumors are a group of tumors originated from the mesenchymal stem cells of the gastrointestinal tract, consisting of gastrointestinal stromal tumors (GIST), leiomyomas or leiomyosarcomas or schwannomas. Gastric schwannoma is a very rare gastrointestinal mesenchymal tumor, which represents only 0.2% of all gastric tumors and 4% of all benign gastric neoplasms. We report a 24-year-old girl who suffered from an episode of upper gastrointestinal bleeding. The endoscopic examination showed a round submucosal tumor with a central ulceration and bleeding over the high body of the stomach. Surgical resection of the tumor was performed. The pathological examination revealed a picture of spindle cell tumor that was strongly positive for S-100 protein stain, and non-reactive for CD34, CD117, actin, HHF-35, desmin, melan-A and HMB-45, consistent with gastric schwannoma. The literature is reviewed.
胃肠道间质瘤是一组起源于胃肠道间充质干细胞的肿瘤，包括胃肠道间质瘤（GIST）、平滑肌瘤或平滑肌肉瘤或神经鞘瘤。胃神经鞘瘤是一种非常罕见的胃肠道间质瘤，仅占所有胃肿瘤的0.2%，占所有胃良性肿瘤的4%。我们报告一名24岁女孩，她曾发生过上消化道出血。内镜检查显示胃体上部有一个圆形黏膜下肿瘤，中央有溃疡和出血。对该肿瘤进行了手术切除。病理检查显示为梭形细胞瘤，S-100蛋白染色呈强阳性，而对CD34、CD117、肌动蛋白、HHF-35、结蛋白、黑素A和HMB-45无反应，符合胃神经鞘瘤。本文对相关文献进行了综述。
