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罕见直肠弹力纤维瘤:诊断挑战与病例报告

Rare rectal elastofibroma: diagnostic challenges and case report.

作者信息

Xiang Chen-Xin, Long Yu, Xiang Yi-Ning, Huang Fei, Ke Yun, Yao Yi-Ran, Zhen Yun-Huan

机构信息

Department of Colorectal Surgery, The Affiliated Hospital of Guizhou Medical University, No. 16 Beijing Road, Yunyan District, Guiyang, 550001, Guizhou, China.

Department of Colorectal Surgery, Guizhou Medical University, Guiyang, 550001, Guizhou, China.

出版信息

Discov Oncol. 2025 May 19;16(1):815. doi: 10.1007/s12672-025-02556-6.

DOI:10.1007/s12672-025-02556-6
PMID:40388002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12089562/
Abstract

Elastofibroma (EF) is a rare soft tissue tumor that typically occurs in the scapular region, with its occurrence in the rectum being extremely uncommon. In this report, we present a case of rectal EF in a 72-year-old female, which was definitively diagnosed through histopathology, immunohistochemistry, and special staining analyses. This case emphasizes the diagnostic challenges posed by rectal EF and underscores the necessity of histopathological and immunohistochemical assessment in distinguishing it from other spindle cell neoplasms, particularly when imaging findings are inconclusive.

摘要

弹力纤维瘤(EF)是一种罕见的软组织肿瘤,通常发生于肩胛区,极少发生于直肠。在本报告中,我们呈现了一例72岁女性直肠弹力纤维瘤病例,通过组织病理学、免疫组织化学及特殊染色分析得以明确诊断。该病例强调了直肠弹力纤维瘤所带来的诊断挑战,并凸显了组织病理学和免疫组织化学评估在鉴别其与其他梭形细胞肿瘤时的必要性,尤其是在影像学检查结果不明确的情况下。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86cd/12089562/7b9bb1ddf1f5/12672_2025_2556_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86cd/12089562/c87197435bf9/12672_2025_2556_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86cd/12089562/680d6f486a24/12672_2025_2556_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86cd/12089562/fbdb4b46011e/12672_2025_2556_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86cd/12089562/d2dff9234be5/12672_2025_2556_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86cd/12089562/7b9bb1ddf1f5/12672_2025_2556_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86cd/12089562/c87197435bf9/12672_2025_2556_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86cd/12089562/680d6f486a24/12672_2025_2556_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86cd/12089562/fbdb4b46011e/12672_2025_2556_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86cd/12089562/d2dff9234be5/12672_2025_2556_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86cd/12089562/7b9bb1ddf1f5/12672_2025_2556_Fig5_HTML.jpg

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本文引用的文献

1
Isolated Elastofibroma of the Thigh: A Case Report.大腿孤立性弹力纤维瘤:一例报告
Cureus. 2023 Jul 20;15(7):e42174. doi: 10.7759/cureus.42174. eCollection 2023 Jul.
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CD34 positive cells as endothelial progenitor cells in biology and medicine.CD34阳性细胞作为生物学和医学中的内皮祖细胞。
Front Cell Dev Biol. 2023 Apr 17;11:1128134. doi: 10.3389/fcell.2023.1128134. eCollection 2023.
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European Neuroendocrine Tumor Society (ENETS) 2023 guidance paper for digestive neuroendocrine carcinoma.欧洲神经内分泌肿瘤学会(ENETS)2023年消化神经内分泌癌指南文件
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Comprehensive immunohistochemical analysis based on the origin of leiomyosarcoma.基于平滑肌肉瘤起源的全面免疫组织化学分析。
Pol J Pathol. 2022;73(3):233-243. doi: 10.5114/pjp.2022.124478.
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EUS-guided intra-tumoral therapies.EUS 引导下的肿瘤内治疗。
Best Pract Res Clin Gastroenterol. 2022 Sep-Dec;60-61:101817. doi: 10.1016/j.bpg.2022.101817. Epub 2022 Dec 14.
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Neuroendocrine tumor theranostics.神经内分泌肿瘤的治疗与诊断。
Cancer Sci. 2022 Jun;113(6):1930-1938. doi: 10.1111/cas.15327. Epub 2022 Apr 11.
7
JNETS clinical practice guidelines for gastroenteropancreatic neuroendocrine neoplasms: diagnosis, treatment, and follow-up: a synopsis.JNETS 胃肠胰神经内分泌肿瘤临床实践指南:诊断、治疗和随访:概要。
J Gastroenterol. 2021 Nov;56(11):1033-1044. doi: 10.1007/s00535-021-01827-7. Epub 2021 Sep 29.
8
Elastofibroma Dorsi, a Rare Condition, with Challenging Diagnosis. Case Report and Literature Review.背部弹力纤维瘤,一种罕见病症,诊断颇具挑战。病例报告及文献综述
Medicina (Kaunas). 2021 Apr 12;57(4):370. doi: 10.3390/medicina57040370.
9
Subungual Elastofibroma.甲下弹力纤维瘤
Skin Appendage Disord. 2021 Jan;7(1):50-53. doi: 10.1159/000510857. Epub 2020 Oct 26.
10
Identification of elastofibroma and elastofibroma-like lesions in cases diagnosed as oral fibromas.在诊断为口腔纤维瘤的病例中识别弹性纤维瘤和弹性纤维瘤样病变。
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