Huang Nicole, Chou Yiing-Jenq, Chang Hong-Jen, Ho Monto, Morlock Laura
Department of Health Education, National Taiwan Normal University, Taipei, Taiwan.
Fam Pract. 2005 Apr;22(2):160-7. doi: 10.1093/fampra/cmh734. Epub 2005 Feb 18.
Imprudent prescribing of antibiotics in ambulatory care in Asia is of great concern. However, an adequate understanding of factors associated with antibiotic prescribing patterns in Asia has not been achieved.
Our aim was to identify patient and physician characteristics that influence antibiotic prescribing for adults with nasopharyngitis (common colds), upper respiratory tract infections (URIs) or bronchitis in Taiwan.
Generalized Estimating Equations (GEE) were used to analyze all 128,260 episodes of common colds, URIs and bronchitis generated by a random sample of 137,935 adult National Health Insurance (NHI) beneficiaries (> or = 18 years old) in Taiwan in 2000.
Multivariate analysis results revealed substantial variations across different physician groups. Physician age and accreditation level of the physician's practice setting were the characteristics most associated with prescribing of antibiotics at the initial encounters for these episodes of care. Urban practising physicians (adjusted OR 1.69, 95% CI 1.29-2.21) and those who were self-dispensing or with on-site pharmacists (adjusted OR 1.32, 95% CI 1.19-1.46) were also higher prescribers of antibiotics for adults. Other significant physician predictors included physician specialty, patient volume, and ownership of practice setting.
Results suggest that both accessibility to updated medical information and economic incentives of the attending physician may shape prescribing of antibiotics in ambulatory care in Taiwan. Interventions should be developed to influence these modifiable factors to reduce antibiotic prescriptions of questionable value.
在亚洲,门诊医疗中抗生素的不合理使用令人深感担忧。然而,对于亚洲地区抗生素处方模式相关因素仍缺乏充分了解。
我们的目的是确定影响台湾地区成人鼻咽炎(普通感冒)、上呼吸道感染(URIs)或支气管炎抗生素处方的患者和医生特征。
采用广义估计方程(GEE)分析了2000年台湾地区137,935名年龄≥18岁的成年国民健康保险(NHI)受益人的随机样本产生的128,260例普通感冒、URIs和支气管炎病例。
多变量分析结果显示不同医生群体之间存在显著差异。医生年龄和医生执业机构的认证水平是这些护理阶段初次就诊时与抗生素处方最相关的特征。城市执业医生(调整后的OR为1.69,95%CI为1.29 - 2.21)以及自行配药或配备现场药剂师的医生(调整后的OR为1.32,95%CI为1.19 - 1.46)也是成人抗生素的高处方者。其他显著的医生预测因素包括医生专业、患者数量和执业机构的所有权。
结果表明,主治医生获取最新医学信息的便利性和经济激励因素可能会影响台湾地区门诊医疗中抗生素的处方。应制定干预措施来影响这些可改变的因素,以减少价值存疑的抗生素处方。