Hauner H, von Ferber L, Köster I
Klinische Abteilung des Diabetes-Forschungsinstituts, Medizinische Fakultät der Universität Düsseldorf.
Dtsch Med Wochenschr. 1992 Apr 24;117(17):645-50. doi: 10.1055/s-2008-1062359.
All records relating to medical prescriptions and services relating to diabetes for a representative sample (n = 6478) of inhabitants of Dortmund in 1988, who were members of the Local Health Insurance in Dortmund, were analysed. 264 patients (4.08%) were receiving antidiabetic drugs during that year, 198 (3.06%) oral ones, 42 (0.65%) insulin and 24 (0.37%) both. 12.41% of all those insured over the age of 60 were on antidiabetic drugs, more women than men (5.08 vs 2.94%; P less than 0.001). The most frequently used oral antidiabetics were sulphonylurea ones (95.1%), while the proportion of biguanides was only 4.4%. On the basis of established diagnosis, regular blood sugar and HbA1 tests, as well as optic fundi examination, a further 104 persons (1.60%) are assumed to have diabetes but not treated by drugs. This sample indicates an overall prevalence of diabetes of 5.68% among the population. Relating it to the age and sex pattern of the population of the Federal Republic of Germany this corresponds to a prevalence of diagnosed diabetes of 4.82%. Thus there are probably a little less than 4 million diabetic citizens of the Federal Republic of Germany.
对1988年多特蒙德市参加当地医疗保险的具有代表性的6478名居民的所有糖尿病医疗处方及相关服务记录进行了分析。当年,264名患者(4.08%)正在接受抗糖尿病药物治疗,其中198名(3.06%)使用口服药物,42名(0.65%)使用胰岛素,24名(0.37%)两者都用。60岁以上所有参保人员中,12.41%正在使用抗糖尿病药物,女性多于男性(5.08%对2.94%;P<0.001)。最常用的口服抗糖尿病药物是磺脲类(95.1%),而双胍类药物的使用比例仅为4.4%。根据既定诊断、定期血糖和糖化血红蛋白检测以及眼底检查,另有104人(1.60%)被认为患有糖尿病但未接受药物治疗。该样本表明该人群中糖尿病的总体患病率为5.68%。将其与德意志联邦共和国人口的年龄和性别模式相关联,这相当于已诊断糖尿病的患病率为4.82%。因此,德意志联邦共和国可能有不到400万糖尿病患者。