Schoot D C, Pache T D, Hop W C, de Jong F H, Fauser B C
Department of Obstetrics and Gynecology A, Dijkzigt University Hospital, Rotterdam, The Netherlands.
Fertil Steril. 1992 May;57(5):1117-20. doi: 10.1016/s0015-0282(16)55035-3.
Data presented in this study indicate that ovulation can be induced in patients with PCOS using a GnRH analogue combined with hMG in a decreasing dose regimen. Based on the observed decline in functional, medium sized follicles in the late follicular phase, it may be speculated that the risk of ovarian hyperstimulation during gonadotropin induction of ovulation in patients with PCOS can be reduced.
本研究中呈现的数据表明,使用促性腺激素释放激素(GnRH)类似物联合递减剂量方案的人绝经期促性腺激素(hMG),可诱导多囊卵巢综合征(PCOS)患者排卵。基于在卵泡晚期观察到的功能性中等大小卵泡数量下降的情况,可以推测,PCOS患者在使用促性腺激素诱导排卵期间发生卵巢过度刺激综合征的风险可能会降低。