Jolivet G, Devinoy E, Fontaine M L, Houdebine L M
Unité de Différenciation Cellulaire, Institut National de la Recherche Agronomique, Jouy en Josas, France.
Gene. 1992 Apr 15;113(2):257-62. doi: 10.1016/0378-1119(92)90404-d.
The complete nucleotide sequence of the entire rabbit alpha s1-casein-encoding gene Aslca and its flanking regions was determined. These data represent the first complete primary sequence of an Aslca gene. The gene consists of 19 exons spread over 16 kb. Highly conserved sequences were found between this gene and other casein-encoding genes mainly upstream from the gene from position -180 to -10. Several repeated interspersed elements of unknown function were also identified within introns.
测定了整个兔αs1-酪蛋白编码基因Aslca及其侧翼区域的完整核苷酸序列。这些数据代表了Aslca基因的首个完整一级序列。该基因由分布在16 kb上的19个外显子组成。在该基因与其他酪蛋白编码基因之间,主要在基因上游从-180位到-10位发现了高度保守序列。在内含子中还鉴定出了几个功能未知的重复散布元件。