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[老年患者的药理学特点及问题]

[Pharmacological peculiarities and problems with older patients].

作者信息

Kratz C D, Schleppers A, Iber T, Geldner G

机构信息

Klinik für Anästhesie und Intensivtherapie, Klinikum der Philipps-Universität, Marburg.

出版信息

Anaesthesist. 2005 May;54(5):467-75. doi: 10.1007/s00101-005-0810-9.

DOI:10.1007/s00101-005-0810-9
PMID:15726243
Abstract

Because of demographic developments, the fraction of the German population over 65 years of age in the year 2025 will have risen to 20% and will continue to rise so that in 2030 this number will have doubled compared to today's numbers. This has a huge impact on the requirements for anaesthesiologic procedures. In addition to the frequent multi-morbidity in this age group, physiologic changes also occur in the elderly which have to be taken into consideration during the entire perioperative management of these patients. Renal, cardiovascular and hepatic function are impaired in many elderly patients. A major concern in addition to cardiovascular and operative complications is the postoperative cognitive dysfunction (POCD), not only because of its implications for the patient but also because of economical consequences. Regional anaesthesia has some benefits when compared to general anaesthesia as it leads to a reduction in thromboembolic and respiratory complications.

摘要

由于人口结构的变化,到2025年,德国65岁以上人口的比例将升至20%,并将持续上升,到2030年,这一数字将比目前翻一番。这对麻醉程序的需求产生了巨大影响。除了该年龄组常见的多种疾病外,老年人还会出现生理变化,在这些患者的整个围手术期管理过程中必须予以考虑。许多老年患者的肾功能、心血管功能和肝功能都有所受损。除了心血管和手术并发症外,术后认知功能障碍(POCD)也是一个主要问题,这不仅是因为它对患者的影响,还因为其经济后果。与全身麻醉相比,区域麻醉有一些益处,因为它可减少血栓栓塞和呼吸系统并发症。

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[Anesthesia for geriatric patients. Part 1: age, organ function and typical diseases].老年患者的麻醉。第1部分:年龄、器官功能及典型疾病
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[Spectrum of patients in prehospital emergency services. What has changed over the last 20 years?].[院前急救服务中的患者谱。过去20年发生了哪些变化?]

本文引用的文献

1
Anaesthesia and the elderly.麻醉与老年人
Curr Opin Anaesthesiol. 2001 Dec;14(6):679-84. doi: 10.1097/00001503-200112000-00014.
2
Anaesthesia in the older patient.老年患者的麻醉
Curr Opin Clin Nutr Metab Care. 2005 Jan;8(1):17-21. doi: 10.1097/00075197-200501000-00004.
3
[Use of opioids in the elderly -- pharmacokinetic and pharmacodynamic considerations].[老年人使用阿片类药物——药代动力学和药效学考量]
Anaesthesist. 2006 Nov;55(11):1157-65. doi: 10.1007/s00101-006-1106-4.
Anasthesiol Intensivmed Notfallmed Schmerzther. 2004 Sep;39(9):527-37. doi: 10.1055/s-2004-825883.
4
[Anaesthesia in cataract surgery for elderly people].[老年人白内障手术中的麻醉]
Anasthesiol Intensivmed Notfallmed Schmerzther. 2004 May;39(5):276-80. doi: 10.1055/s-2004-814436.
5
Fluid and electrolytes in the elderly.老年人的体液与电解质
Curr Opin Clin Nutr Metab Care. 2004 Jan;7(1):27-33. doi: 10.1097/00075197-200401000-00006.
6
Recovery of elderly patients from two or more hours of desflurane or sevoflurane anaesthesia.老年患者从两小时或更长时间的地氟烷或七氟烷麻醉中恢复。
Br J Anaesth. 2003 Oct;91(4):502-6. doi: 10.1093/bja/aeg221.
7
Cognitive function after anaesthesia in the elderly.老年人麻醉后的认知功能。
Best Pract Res Clin Anaesthesiol. 2003 Jun;17(2):259-72. doi: 10.1016/s1521-6896(03)00005-3.
8
Pharmacodynamics in the elderly.老年人的药效学
Best Pract Res Clin Anaesthesiol. 2003 Jun;17(2):207-18. doi: 10.1016/s1521-6896(03)00008-9.
9
Priorities in perioperative geriatrics.围手术期老年医学的优先事项。
Anesth Analg. 2003 Jun;96(6):1823-1836. doi: 10.1213/01.ANE.0000063822.02757.41.
10
Does anaesthesia cause postoperative cognitive dysfunction? A randomised study of regional versus general anaesthesia in 438 elderly patients.麻醉会导致术后认知功能障碍吗?一项针对438例老年患者的区域麻醉与全身麻醉的随机研究。
Acta Anaesthesiol Scand. 2003 Mar;47(3):260-6. doi: 10.1034/j.1399-6576.2003.00057.x.