Kreidieh I, Davies D W, Lim R, Nathan A W, Dymond D S, Banim S O
Department of Cardiology, St. Bartholomew's Hospital, London, UK.
Int J Cardiol. 1992 May;35(2):147-52. doi: 10.1016/0167-5273(92)90171-x.
Percutaneous transluminal coronary angioplasty was attempted with elective percutaneous intra-aortic balloon pump support in 21 patients (mean age 60 years, range 40-82; 18 males) with unstable angina (n = 2), multivessel coronary disease requiring multivessel angioplasty (n = 2), severe left ventricular dysfunction (ejection fraction 10-30%; n = 16) or ventricular fibrillation at diagnostic angiography (n = 1). Fourteen patients had 3-vessel disease (1 with vein grafts also diseased), 6 had 2-vessel disease and 1 had isolated left anterior descending disease. Twenty-five procedures were performed (one in 18 patients, two in 2 patients and three in one patient) on 42 lesions in 34 vessels/grafts. There was no angioplasty-related death. Successful dilatation was achieved in 38/42 lesions (90%) in 21/25 procedures (84%) without major complication. Three procedures were complicated: one by major coronary dissection without sequelae, one by haemodynamic deterioration due to distal occlusion and one by an unstable residual stenosis in the attempted vessel necessitating urgent bypass surgery. The only complication related to the intra-aortic balloon pump was local haematoma in 2 patients. In conclusion, elective intra-aortic balloon pump support may be safely used to stabilise high-risk patients undergoing coronary angioplasty, leading to a satisfactory primary success rate.
对21例患者(平均年龄60岁,范围40 - 82岁;18例男性)尝试进行经皮腔内冠状动脉成形术,并选择性应用经皮主动脉内球囊反搏支持,这些患者患有不稳定型心绞痛(2例)、需要多支血管成形术的多支冠状动脉疾病(2例)、严重左心室功能障碍(射血分数10% - 30%;16例)或诊断性血管造影时出现心室颤动(1例)。14例患者患有三支血管病变(1例静脉桥血管也有病变),6例患有两支血管病变,1例患有孤立的左前降支病变。对34支血管/移植物中的42处病变进行了25次操作(18例患者进行1次,2例患者进行2次,1例患者进行3次)。没有与血管成形术相关的死亡。21次操作中的21次(84%)对42处病变中的38处(90%)成功进行了扩张,无重大并发症。3次操作出现并发症:1次出现无后遗症的严重冠状动脉夹层,1次因远端闭塞导致血流动力学恶化,1次在尝试治疗的血管中出现不稳定的残余狭窄,需要紧急进行搭桥手术。与主动脉内球囊反搏相关的唯一并发症是2例患者出现局部血肿。总之,选择性主动脉内球囊反搏支持可安全用于稳定接受冠状动脉成形术的高危患者,获得满意的初次成功率。