Anwar A, Mooney M R, Stertzer S H, Mooney J F, Shaw R E, Madison J D, VanTassel R A, Murphy M C, Myler R K
San Francisco Heart Institute, Daly City, California.
J Invasive Cardiol. 1990 Jul-Aug;2(4):175-80.
A two-center elective coronary angioplasty experience with intra-aortic balloon pump support for patients with severe left ventricular dysfunction is reported. To prevent hemodynamic collapse, an intra-aortic balloon pump was inserted percutaneously before coronary angioplasty in 97 patients with a left ventricular ejection fraction less than 35% (26% of whom had ejection fractions less than 25%). The cohort was predominantly male (71%) with a mean age of 64 +/- 9 years. Angioplasty was successfully performed in 83 (85.6%) patients and 80 (82.5%) of these successful patients were discharged from the hospital. Seven patients had unsuccessful angioplasty without a major cardiac event. Seven patients (7.2%) suffered a major cardiac event; 4 had emergent coronary bypass surgery with q-wave infarction, 2 had uneventful emergency coronary bypass surgery, and one patient died in the operating room after a failed angioplasty. Using logistic regression analysis, the presence of multivessel disease and a history of prior myocardial infarction were associated with more complications during angioplasty (p less than 0.05). Intra-aortic balloon pump placement did not interfere with the angioplasty procedure. Two patients had limb ischemia which resolved when the intra-aortic balloon pump was removed. Of the 80 successful patients discharged, 72 were followed for a mean of 22 months. At the latest follow-up, 52 had not suffered a myocardial infarction and were alive. Of the 20 late deaths, 16 were cardiac and 4 non-cardiac.(ABSTRACT TRUNCATED AT 250 WORDS)
本文报告了两中心针对严重左心室功能不全患者,在主动脉内球囊反搏支持下进行选择性冠状动脉成形术的经验。为防止血流动力学崩溃,在冠状动脉成形术前,对97例左心室射血分数低于35%的患者经皮插入主动脉内球囊反搏(其中26%的患者射血分数低于25%)。该队列主要为男性(71%),平均年龄64±9岁。83例(85.6%)患者成功进行了冠状动脉成形术,其中80例(82.5%)成功患者出院。7例患者冠状动脉成形术未成功,但未发生重大心脏事件。7例患者(7.2%)发生了重大心脏事件;4例因q波梗死接受了急诊冠状动脉搭桥手术,2例接受了顺利的急诊冠状动脉搭桥手术,1例患者在冠状动脉成形术失败后死于手术室。使用逻辑回归分析,多支血管病变和既往心肌梗死病史与冠状动脉成形术期间更多并发症相关(p<0.05)。主动脉内球囊反搏的放置未干扰冠状动脉成形术操作。2例患者出现肢体缺血,在移除主动脉内球囊反搏后症状缓解。在80例成功出院的患者中,72例接受了平均22个月的随访。在最近一次随访时,52例未发生心肌梗死且存活。在20例晚期死亡患者中,16例为心脏原因,4例为非心脏原因。(摘要截短于250字)