Cranswick R, Davis R, Jones M, Hunyor S N
Department of Cardiology and Health Information Systems, Royal North Shore Hospital, St Leonards, Australia.
Int J Cardiol. 1992 May;35(2):241-51. doi: 10.1016/0167-5273(92)90183-4.
Infarct size may influence left ventricular filling after acute myocardial infarction. Pulsed Doppler transmitral flow velocities were compared in 47 patients at 7 +/- 6 days following acute myocardial infarction and 47 age-matched controls. Patients were stratified by angiographic infarct size into Groups I, II, III (corresponding angiographic hypokinetic scores less than 2; 2-2.99; greater than or equal to 3 SD/cord). Early diastolic transmitral Doppler flow velocities did not differ between infarct groups but atrial transmitral Doppler flow measurements did: peak A velocity (p = 0.001), A velocity time integral (p less than 0.001), and total velocity time integral (p = 0.001). Compared to controls atrial transmitral Doppler flow was augmented in Group I, whilst atrial and total transmitral Doppler flow were depressed in Group III. Peak A velocity and A velocity time integral were inversely related to infarct size (R = -0.44 to -0.54) and directly to left ventricular ejection fraction (R = 0.59 to 0.65). Large infarct size following myocardial infarction is associated with lower atrial and total transmitral Doppler flow velocities.
梗死面积可能会影响急性心肌梗死后的左心室充盈。对47例急性心肌梗死后7±6天的患者及47例年龄匹配的对照者的脉冲多普勒二尖瓣血流速度进行了比较。根据血管造影梗死面积将患者分为I、II、III组（相应的血管造影运动减弱评分分别小于2；2-2.99；大于或等于3个标准差/节段）。梗死组之间舒张早期二尖瓣多普勒血流速度无差异，但二尖瓣心房多普勒血流测量结果有差异：A峰速度（p = 0.001）、A速度时间积分（p < 0.001）和总速度时间积分（p = 0.001）。与对照组相比，I组二尖瓣心房多普勒血流增加，而III组二尖瓣心房和总血流减少。A峰速度和A速度时间积分与梗死面积呈负相关（R = -0.44至-0.54），与左心室射血分数呈正相关（R = 0.59至0.65）。心肌梗死后大面积梗死与较低的二尖瓣心房和总血流速度相关。
