Hourihane J O'B, Rhodes H L, Jones A M, Veys P, Connett G J
Division of Infection, Inflammation and Repair, University of Southampton, Southampton, UK.
Allergy. 2005 Apr;60(4):536-7. doi: 10.1111/j.1398-9995.2005.00752.x.
Peanut allergy is a severe and life-threatening form of food allergy. Treatments are being developed but the mainstays of current management remain avoidance of peanut and appropriate use of rescue medication. We report the case of a boy with peanut allergy who required a bone marrow transplant (BMT) for combined immunodeficiency. A food challenge, 2 years after transplant, showed that his peanut allergy had resolved. Allergic disorders constitute a form of immune deviation and while we do not advocate BMT as a treatment for peanut allergy, we believe this case provides an insight into the basic mechanisms involved in food allergy.
花生过敏是一种严重且危及生命的食物过敏形式。治疗方法正在研发中，但目前管理的主要手段仍是避免食用花生以及合理使用急救药物。我们报告了一名患有花生过敏的男孩的病例，他因联合免疫缺陷需要进行骨髓移植（BMT）。移植后两年的食物激发试验表明，他的花生过敏已得到缓解。过敏性疾病构成了一种免疫偏差形式，虽然我们不主张将骨髓移植作为花生过敏的治疗方法，但我们认为这个病例为深入了解食物过敏所涉及的基本机制提供了线索。
