Majola A, Vainionpää S, Vihtonen K, Vasenius J, Törmälä P, Rokkanen P
Department of Orthopaedics and Traumatology, University Central Hospital, Helsinki, Finland.
Int Orthop. 1992;16(1):101-8. doi: 10.1007/BF00182996.
Osteotomies of the femoral shaft in rabbits were fixed with intramedullary rods made of poly-L-lactic acid (SR-PLLA) and poly-DL/L-lactic acid (SR-PDLLA/PLLA). Follow up was from one week to 2 years. In the PLLA group, in 37 out of 40 osteotomies the fixation was firm and the bone was united. In the PDLLA/PLLA group, the fixation was firm in 30 out of 45, but in 13 of these angular deformity of more than 10 degrees had occurred. The fixation had failed in 15. No inflammatory or foreign body reaction was seen in either group. This study demonstrates that SR-PLLA rods are suitable fixation for cortical osteotomies in rabbits.
用聚-L-乳酸(SR-PLLA)和聚-DL/L-乳酸(SR-PDLLA/PLLA)制成的髓内棒固定兔股骨干截骨术。随访时间为1周-2年。在PLLA组,40例截骨术中37例固定牢固,骨愈合。在PDLLA/PLLA组,45例中有30例固定牢固,但其中13例出现了超过10度的角形畸形。15例固定失败。两组均未观察到炎症或异物反应。本研究表明,SR-PLLA棒适用于兔皮质骨截骨术的固定。