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手部湿疹严重程度指数(HECSI):一种用于手部湿疹临床评估的评分系统。观察者间及观察者内可靠性研究。

The hand eczema severity index (HECSI): a scoring system for clinical assessment of hand eczema. A study of inter- and intraobserver reliability.

作者信息

Held E, Skoet R, Johansen J D, Agner T

机构信息

National Allergy Research Centre and Department of Dermatology, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

出版信息

Br J Dermatol. 2005 Feb;152(2):302-7. doi: 10.1111/j.1365-2133.2004.06305.x.

Abstract

BACKGROUND

There is a need for a standardized clinical grading system for a more objective and accurate assessment of the severity of hand eczema (HE).

OBJECTIVES

To develop and validate a scoring system called the hand eczema severity index (HECSI) designed for clinical assessment of HE.

METHODS

Twelve dermatologists (observers) assessed 15 HE patients twice, with an interval of 30 min. The study was performed blinded for the observers, and only the hands and wrists of the patients were visible to the observers. Agreement between the observers was determined by using the intraclass correlation coefficient (ICC), which is the correlation between (single) ratings of the same patient.

RESULTS

ICC for total HECSI score was 0.79 at the first assessment and 0.84 at the second assessment. ICC for intraobserver agreement was 0.90.

CONCLUSIONS

Overall excellent agreement existed for both inter- and intraobserver reliability and the scoring system is suggested for use in future clinical studies on HE. Because HECSI is an entirely objective assessment of clinical signs, in addition, inclusion of patient-rated symptoms should be considered.

摘要

背景

需要一种标准化的临床分级系统,以便更客观、准确地评估手部湿疹(HE)的严重程度。

目的

开发并验证一种名为手部湿疹严重程度指数(HECSI)的评分系统,用于手部湿疹的临床评估。

方法

12名皮肤科医生(观察者)对15名手部湿疹患者进行了两次评估,间隔30分钟。研究对观察者设盲,观察者只能看到患者的手部和腕部。观察者之间的一致性通过组内相关系数(ICC)来确定,ICC是同一患者(单次)评分之间的相关性。

结果

首次评估时,HECSI总分的ICC为0.79,第二次评估时为0.84。观察者内一致性的ICC为0.90。

结论

观察者间和观察者内的可靠性总体上具有良好的一致性,建议该评分系统用于未来手部湿疹的临床研究。此外,由于HECSI是对临床体征的完全客观评估,应考虑纳入患者自评症状。

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