Jeong Y, Park K C, Cho S S, Kim E J, Kang S J, Kim S E, Kang E, Na D L
Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Neurology. 2005 Feb 22;64(4):734-6. doi: 10.1212/01.WNL.0000152047.58767.9D.
Frontotemporal dementia (FTD) often coexists with motor neuron disease (MND). To characterize glucose hypometabolism in patients with FTD with MND (FTD/MND), the authors compared the glucose metabolism of 8 patients with FTD/MND with that of 29 patients with FTD. All of the patients with FTD/MND showed glucose hypometabolism only in the frontal area, whereas most patients with FTD had hypometabolism in the frontal and temporal areas. FTD/MND also showed a more symmetric pattern of glucose hypometabolism than FTD.
额颞叶痴呆(FTD)常与运动神经元病(MND)共存。为了描述伴运动神经元病的额颞叶痴呆(FTD/MND)患者的葡萄糖代谢减退情况,作者比较了8例FTD/MND患者与29例FTD患者的葡萄糖代谢情况。所有FTD/MND患者仅在额叶出现葡萄糖代谢减退,而大多数FTD患者在额叶和颞叶均有代谢减退。与FTD相比,FTD/MND的葡萄糖代谢减退模式也更具对称性。