Munster A M
Johns Hopkins University School of Medicine, Baltimore, Maryland.
J Burn Care Rehabil. 1992 Jan-Feb;13(1):124-6. doi: 10.1097/00004630-199201000-00028.
This article updates our single-center experience, which was reported in 1990 (Munster AM, Weiner S, Spence RB. Cultured epidermis for the coverage of massive burns: a single center experience. Ann Surg 1990;211:676-80). Current data include data from the time period 1988 to 1990. To date, 10 patients with a mean surface burn of 71.6% were partially treated with cultured epidermal autograft, and no deaths occurred. A group of 41 control patients (partly retrospective and partly concurrent but not randomized) sustained a mean burn of 54.7% body surface area. There were 14 deaths (p less than 0.05 versus the group that received cultured epidermal autograft). No major problems with late graft fragility (up to 2 years) or contracture were noted.
本文更新了我们于1990年报道的单中心经验(Munster AM,Weiner S,Spence RB。培养表皮用于大面积烧伤的覆盖:单中心经验。《外科学年鉴》1990年;211:676 - 80)。当前数据包括1988年至1990年期间的数据。迄今为止,10例平均烧伤面积为71.6%的患者接受了培养表皮自体移植部分治疗,且无死亡病例。一组41例对照患者(部分为回顾性,部分为同期但未随机分组)平均烧伤面积为体表面积的54.7%。有14例死亡(与接受培养表皮自体移植的组相比,p<0.05)。未发现晚期移植物脆性(长达2年)或挛缩的重大问题。