Singh Neeru, Saxena Ajay
Malaria Research Centre Field Station, Regional Medical Research Centre Complex, Jabalpur, Madhya Pradesh, India.
Am J Trop Med Hyg. 2005 Jan;72(1):26-9.
Logistic, economic, and technical factors limit rapid access to microscopic confirmation of malaria in many tropical countries, including India. The occurrence of high-grade fever and three deaths during the hot summer months in some forest migrants created an emergency situation in Jabalpur in central India. A cheap and rapid malaria test, Paracheck Pf, was tested in this group of migrants in parallel with microscopy. The indigenous population at the site of occupational activities of these migrants approximately 250 km from Jabalpur was also screened by both methods. The results of this field investigation are very encouraging. Among migrants, the test had a sensitivity of 100% and a specificity of 67%. The positive and negative predictive values were 94% and 100%, respectively. Among indigenous population, the corresponding values were 100%, 97.3%, 98.4%, and 100%, respectively, indicating the usefulness of test as a diagnostic tool for providing on-site confirmation of symptomatic diagnosis of Plasmodium falciparum malaria.
在包括印度在内的许多热带国家，后勤、经济和技术因素限制了对疟疾进行快速显微镜确诊。印度中部一些森林移民在炎热的夏季出现高烧和三人死亡的情况，在贾巴尔普尔引发了紧急状况。一种廉价且快速的疟疾检测方法——疟原虫检测试剂盒（Paracheck Pf）与显微镜检测法同时在这群移民中进行了测试。在距离贾巴尔普尔约250公里的这些移民职业活动地点的当地居民也用这两种方法进行了筛查。此次现场调查的结果非常令人鼓舞。在移民中，该检测方法的灵敏度为100%，特异性为67%。阳性预测值和阴性预测值分别为94%和100%。在当地居民中，相应的值分别为100%、97.3%、98.4%和100%，这表明该检测方法作为一种诊断工具，对于现场确诊恶性疟原虫疟疾的症状性诊断是有用的。
