Skárka L, Ost'ádal B
Centrum experimentálního výzkumu chorob srdce a cév, Fyziologický ústav Akademie vĕd Ceské republiky, Praha.
Cas Lek Cesk. 2004;143(12):809-16.
Besides their traditional role as the energy factory of the cell, mitochondria play an important role in other aspects of cardiac cell functioning under physiological and pathological conditions. They are involved in the regulation of calcium homeostasis, production of reactive oxygen species as well as in the process of cardiac cell death. Recently, the interest in their participation in ischemia-reperfusion injury and potential role in cardioprotective mechanisms, with particular attention to developmental aspects has markedly increased.
除了作为细胞能量工厂的传统作用外，线粒体在生理和病理条件下心脏细胞功能的其他方面也发挥着重要作用。它们参与钙稳态的调节、活性氧的产生以及心脏细胞死亡过程。最近，人们对它们参与缺血再灌注损伤以及在心脏保护机制中的潜在作用的兴趣显著增加，尤其关注其发育方面。
