Matsugi Masato, Curran Dennis P
Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.
J Org Chem. 2005 Mar 4;70(5):1636-42. doi: 10.1021/jo048001n.
Light fluorous versions of first- and second-generation Grubbs-Hoveyda metathesis catalysts are introduced. These exhibit the expected reactivity profile, are readily recovered from reaction mixtures by fluorous solid-phase extraction, and can be routinely reused five or more times. The catalysts can be used in a stand alone fashion, or supported on fluorous silica gel.
介绍了第一代和第二代格拉布-霍维达复分解催化剂的轻质氟代版本。这些催化剂表现出预期的反应活性，通过氟代固相萃取可轻松从反应混合物中回收，并且可以常规重复使用五次或更多次。这些催化剂可以单独使用，也可以负载在氟代硅胶上。
