[用于诊断日间嗜睡的简化清醒维持试验的评估]

[Evaluation of a simplified maintenance of wakefulness test for the diagnosis of daytime sleepiness].

作者信息

Luo Yuan-Ming, Zhong Nan-Shan

机构信息

Guangzhou Institute of Respiratory Diseases, Guangzhou 510120, China.

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 2004 Dec;27(12):847-9.

PMID:15730787

Abstract

OBJECTIVE

The purpose of this study was to assess a simplified maintenance of wakefulness test (Oxford SLEep Resistance test, OSLER test) in evaluating excessive daytime sleepiness.

METHODS

Seventy-four snorers with or without obstructive sleep apnea-hypopnea syndrome (OSAHS) were studied. Two OSLER tests were performed in the afternoon with a gap of 30 minutes. Epworth sleepiness scale (ESS) was also recorded. An overnight sleep study using a multi-channel system was performed to distinguish nonapneic snorers (snorer group, n = 43) from OSAHS patients (OSAHS group, n = 31). The OSLER test was repeated in the OSAHS group after two month treatment with nasal continuous positive airway pressure (CPAP).

RESULTS

There was a significant difference in sleep latency measured by the OSLER test between the OSAHS group and the snorer group (16.03 +/- 12.27 vs 25.70 +/- 14.62, P < 0.01). A significant correlation was found between sleep latency and ESS (r = -0.45, P < 0.01). Twenty-five of the 31 patients in the OSAHS group were treated with CPAP for two months. Sleep latency increased from 16.20 +/- 12.98 to 36.38 +/- 21.10 after treatment (P < 0.01).

CONCLUSION

The OSLER test appears useful in assessing excessive daytime sleepiness.

摘要

目的

本研究旨在评估一种简化的清醒维持测试（牛津睡眠抵抗测试，OSLER测试）在评估日间过度嗜睡方面的作用。

方法

对74名有或无阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的打鼾者进行了研究。在下午进行两次OSLER测试，间隔30分钟。同时记录爱泼沃斯嗜睡量表（ESS）。使用多导睡眠监测系统进行整夜睡眠研究，以区分非呼吸暂停性打鼾者（打鼾组，n = 43）和OSAHS患者（OSAHS组，n = 31）。OSAHS组在接受鼻持续气道正压通气（CPAP）治疗两个月后重复进行OSLER测试。

结果

OSAHS组和打鼾组通过OSLER测试测得的睡眠潜伏期有显著差异（16.03±12.27对25.70±14.62，P < 0.01）。睡眠潜伏期与ESS之间存在显著相关性（r = -0.45，P < 0.01）。OSAHS组的31名患者中有25名接受了CPAP治疗两个月。治疗后睡眠潜伏期从16.20±12.98增加到36.38±21.10（P < 0.01）。