Krieger Ana C, Ayappa Indu, Norman Robert G, Rapoport David M, Walsleben Joyce
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Sleep Disorders Center, New York University School of Medicine, New York, NY 10016, USA.
J Sleep Res. 2004 Dec;13(4):407-11. doi: 10.1111/j.1365-2869.2004.00417.x.
The objectives were to evaluate the correlation between sleep onset as defined by the Oxford sleep resistance (OSLER) test and by simultaneous electroencephalography (EEG) and to determine the correlation between sleep latencies measured by the OSLER test and maintenance of wakefulness test (MWT) performed on the same day. This was a prospective, cross-sectional study carried out in a tertiary-care university-based sleep laboratory. Participants were 11 consecutive subjects presenting to the sleep center with clinical indications for nocturnal polysomnography and MWT. The interventions included MWT and OSLER test. Mean sleep latencies for the OSLER and MWT in each subject were closely correlated (ICC = 0.94, [Intra-class correlation]P < 0.05). Sleep latency by OSLER and simultaneous measurement of EEG also had excellent agreement (ICC = 0.91) with a bias of -0.97 min. The OSLER test is a practical and reliable tool for evaluating daytime sleepiness when compared with the MWT. No obvious systematic adaptation was seen during sequential OSLER test performance. Given its portability and minimal technical requirements, the OSLER test may be useful for large-scale applications in the evaluation of daytime wakefulness and vigilance.
本研究旨在评估牛津睡眠抵抗（OSLER）测试所定义的入睡情况与同步脑电图（EEG）之间的相关性，并确定OSLER测试所测量的睡眠潜伏期与同一天进行的清醒维持测试（MWT）之间的相关性。这是一项在以大学为基础的三级医疗睡眠实验室中进行的前瞻性横断面研究。研究对象为11名连续就诊于睡眠中心、有夜间多导睡眠图和MWT临床指征的受试者。干预措施包括MWT和OSLER测试。每个受试者的OSLER和MWT的平均睡眠潜伏期密切相关（组内相关系数[ICC]=0.94，P<0.05）。OSLER测试的睡眠潜伏期与EEG同步测量结果也具有良好的一致性（ICC=0.91），偏差为-0.97分钟。与MWT相比，OSLER测试是评估日间嗜睡的一种实用且可靠的工具。在连续进行OSLER测试过程中未观察到明显的系统适应性。鉴于其便携性和最低技术要求，OSLER测试可能有助于在评估日间清醒和警觉性方面进行大规模应用。
