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对核研究平台8的神经反应遥测(NRT)能力的评估:NRT试验的初步结果。

Evaluation of the neural response telemetry (NRT) capabilities of the nucleus research platform 8: initial results from the NRT trial.

作者信息

Battmer Rolf D, Dillier Norbert, Lai Wai K, Weber Benno P, Brown Carolyn, Gantz Bruce J, Roland J Thomas, Cohen Noel J, Shapiro William, Pesch Joerg, Killian Matthijs J, Lenarz Thomas

机构信息

Medizinische Hochschule Hannover, Hannover, Germany.

出版信息

Int J Audiol. 2004 Dec;43 Suppl 1:S10-5.

Abstract

The purpose of this study was to evaluate the performance of the new features of the Nucleus Research Platform 8 (RP8), a system developed specifically for research purposes The RP8 consists of a research implant, a speech processor and a new NRT software (NRT v4), and includes comparisons of the different artefact-cancellation methods, NRT threshold, and recovery function measurements. The system has new artefact-suppression techniques and new diagnostic capabilities; their performance has been verified in animal experiments. In this study, NRT data were collected from 15 postlingually deafened adult cochlear implant patients intraoperatively and up to 6 months postoperatively after switch-on. The initial investigation in two clinics in Europe focused primarily on the enhanced NRT capabilities Results from the trial in two European clinics indicate that NRT measurements can be obtained with lower noise levels. A comparison of the different artefact-cancellation techniques showed that the forward-masking paradigm implemented in the Nucleus 3 system is still the method of choice. The focus of this report is on recovery function characteristics, which may give insight into auditory nerve fiber properties with regard to higher stimulation rates.

摘要

本研究的目的是评估专门为研究目的开发的Nucleus研究平台8(RP8)新特性的性能。RP8由一个研究植入物、一个语音处理器和一个新的NRT软件(NRT v4)组成,包括对不同伪迹消除方法、NRT阈值和恢复功能测量的比较。该系统具有新的伪迹抑制技术和新的诊断能力;其性能已在动物实验中得到验证。在本研究中,从15名语后聋成年人工耳蜗植入患者术中及开机后长达6个月收集NRT数据。在欧洲的两家诊所进行的初步调查主要集中在增强的NRT能力上。欧洲两家诊所的试验结果表明,可以在较低噪声水平下获得NRT测量值。对不同伪迹消除技术的比较表明,Nucleus 3系统中实施的前向掩蔽范式仍然是首选方法。本报告的重点是恢复功能特征,这可能有助于深入了解关于更高刺激率的听觉神经纤维特性。

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