Ioannidis Alexander S, Speedwell Lynne, Nischal Ken K
Department of Ophthalmology, Great Ormond Street Hospital for Children, London WC1N3JH, UK.
Am J Ophthalmol. 2005 Feb;139(2):356-7. doi: 10.1016/j.ajo.2004.07.044.
To report a case of unilateral keratoconus in a 7- year-old female, secondary to chronic persistent eye-rubbing in the absence of any systemic condition.
Observational case report.
In the case of this child, no organic cause was found to explain the onset of keratoconus other than persistent eye-rubbing in the affected eye.
Nocturnal eye padding was instigated and the condition stabilized. She was reviewed over a 2-year period of follow-up.
Eye-rubbing has been implicated in the pathogenesis of keratoconus. Eye-rubbing is also often a feature of a number of conditions linked to keratoconus such as Down syndrome, atopic keratoconjunctivitis, mental retardation, and Lebers' congenital amaurosis. There are a number of reports linking eye-rubbing and keratoconus in children, typically in relation to these conditions. However, in this case the keratoconus was secondary to chronic and persistent eye-rubbing in a healthy child.
报告一例7岁女性单侧圆锥角膜病例，该病例继发于无任何全身疾病情况下的慢性持续性揉眼。
观察性病例报告。
在该患儿病例中，除患眼持续性揉眼外，未发现其他可解释圆锥角膜发病的器质性病因。
采用夜间眼部包扎，病情稳定。在2年的随访期内对其进行了复查。
揉眼与圆锥角膜的发病机制有关。揉眼也是许多与圆锥角膜相关疾病的常见特征，如唐氏综合征、特应性角结膜炎、智力迟钝和莱伯先天性黑蒙。有许多关于儿童揉眼与圆锥角膜相关的报道，通常与这些疾病有关。然而，在本病例中，圆锥角膜继发于一名健康儿童的慢性持续性揉眼。
