Liu Pen-I, Liu Gin-Chung, Tsai Kun-Bow, Lin Chih-Lung, Hsu Jui-Sheng
Department of Medical Imaging, Kaoshiung Medical University, Chung-Ho Memorial Hospital, Kaoshiung City, Taiwan, R.O.C.
Surg Neurol. 2005 Mar;63(3):285-8; discussion 288-9. doi: 10.1016/j.surneu.2004.03.013.
Intraspinal clear-cell meningioma (CCM) is a rare morphological variant of meningioma with only 16 documented cases. We report one case and review the literature regarding intraspinal CCM.
A 2-year-old boy and a 2-month-old male infant presented with knee pain and leg weakness. Magnetic resonance imaging revealed an intradural extramedullary neoplasm at T10-L1. The patient underwent radical resection of the tumor. Pathology and immunohistochemical study demonstrated a CCM. Unfortunately, the patient had a recurrence 5 years after the operation.
Intraspinal CCMs are very uncommon tumors. They usually show aggressive behavior with local recurrence observed in slightly more than half of all patients. We recommend serial imaging studies every 3 to 6 months during the first several years, after which an annual imaging study should be performed for follow-up.
脊髓内透明细胞型脑膜瘤（CCM）是一种罕见的脑膜瘤形态学变异类型，仅有16例文献报道。我们报告1例病例并复习有关脊髓内CCM的文献。
一名2岁男孩和一名2个月大的男婴表现为膝关节疼痛和腿部无力。磁共振成像显示胸10至腰1水平硬膜内髓外肿瘤。患者接受了肿瘤根治性切除术。病理及免疫组化研究证实为CCM。不幸的是，患者术后5年复发。
脊髓内CCM是非常罕见的肿瘤。它们通常表现出侵袭性，超过半数的患者会出现局部复发。我们建议在最初几年每3至6个月进行系列影像学检查，此后每年进行一次影像学检查以进行随访。
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